The hypothesis that dopamine is important for reward has been proposed in a number of
forms, each of which has been challenged. Normally, rewarding stimuli such as food, water …

Studies addressing behavioral functions of dopamine (DA) in the nucleus accumbens septi
(NAS) are reviewed. A role of NAS DA in reward has long been suggested. However, some …

The anhedonia hypothesis—that brain dopamine plays a critical role in the subjective
pleasure associated with positive rewards—was intended to draw the attention of …

Although the Skinnerian 'Empirical Law of Effect'does not directly consider the fundamental
properties of stimuli that enable them to act as reinforcers, such considerations are critical for …

Amphetamine microinjection into the nucleus accumbens shell enhanced the ability of a
Pavlovian reward cue to trigger increased instrumental performance for sucrose reward in a …

Obesity presents a major health hazard of the 21st century. It promotes co-morbid diseases
such as heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and …

The ability of food to establish and maintain response habits and conditioned preferences
depends largely on the function of brain dopamine systems. While dopaminergic …

Background and objectives The idea that nucleus accumbens (Acb) dopamine transmission
contributes to the neural mediation of reward, at least in a general sense, has achieved wide …

Electrical stimulation of the medial forebrain bundle can reward arbitrary acts or motivate
biologically primitive, species‐typical behaviors like feeding or copulation. The subsystems …

The administration of the dopamine antagonists, pimozide and α-flupenthixol, to rats
reduced Pavlovian–instrumental transfer when a conditioned stimulus (CS) that had been …