Photobiocatalytic strategies for organic synthesis

MA Emmanuel, SG Bender, C Bilodeau… - Chemical …, 2023 - ACS Publications
Biocatalysis has revolutionized chemical synthesis, providing sustainable methods for
preparing various organic molecules. In enzyme-mediated organic synthesis, most reactions …

[HTML][HTML] Review of NAD (P) H-dependent oxidoreductases: Properties, engineering and application

LS Vidal, CL Kelly, PM Mordaka, JT Heap - Biochimica et Biophysica Acta …, 2018 - Elsevier
Abstract NAD (P) H-dependent oxidoreductases catalyze the reduction or oxidation of a
substrate coupled to the oxidation or reduction, respectively, of a nicotinamide adenine …

Selective aerobic oxidation reactions using a combination of photocatalytic water oxidation and enzymatic oxyfunctionalizations

W Zhang, E Fernández-Fueyo, Y Ni, M Van Schie… - Nature …, 2018 - nature.com
Peroxygenases offer an attractive means to address challenges in selective
oxyfunctionalization chemistry. Despite this, their application in synthetic chemistry remains …

Electrochemical transformations catalyzed by cytochrome P450s and peroxidases

N Kumar, J He, JF Rusling - Chemical Society Reviews, 2023 - pubs.rsc.org
Cytochrome P450s (Cyt P450s) and peroxidases are enzymes featuring iron heme cofactors
that have wide applicability as biocatalysts in chemical syntheses. Cyt P450s are a family of …

P450 BM3 (CYP102A1): connecting the dots

CJC Whitehouse, SG Bell, LL Wong - Chemical Society Reviews, 2012 - pubs.rsc.org
P450BM3 (CYP102A1), a fatty acid hydroxylase from Bacillus megaterium, has been
extensively studied over a period of almost forty years. The enzyme has been redesigned to …

Industrial methods for the production of optically active intermediates

M Breuer, K Ditrich, T Habicher, B Hauer… - Angewandte Chemie …, 2004 - Wiley Online Library
Enantiomerically pure amino acids, amino alcohols, amines, alcohols, and epoxides play an
increasingly important role as intermediates in the pharmaceutical industry and …

[图书][B] Modern oxidation methods

JE Bäckvall - 2011 - books.google.com
While rust is an unwanted oxidation reaction, there are also many other useful oxidation
reactions that are extremely important and number among the most commonly used …

Tuning P450 enzymes as oxidation catalysts

R Fasan - Acs Catalysis, 2012 - ACS Publications
The development of catalytic systems for the controlled oxidation of C–H bonds remains a
highly sought-after goal in chemistry owing to the great utility of such transformation toward …

Biocatalysis for pharmaceutical intermediates: the future is now

DJ Pollard, JM Woodley - TRENDS in Biotechnology, 2007 - cell.com
Biocatalysis is continuing to gain momentum and is now becoming a key component in the
toolbox of the process chemist, with a place alongside chemocatalysis and chromatographic …

Selective Catalytic Oxidation of C H Bonds with Molecular Oxygen

E Roduner, W Kaim, B Sarkar, VB Urlacher… - …, 2013 - Wiley Online Library
Although catalytic reductions, cross‐couplings, metathesis, and oxidation of C C double
bonds are well established, the corresponding catalytic hydroxylations of C H bonds in …