Friedländer reaction on 2-amino-3-cyano-4H-pyrans: Synthesis of derivatives of 4H-pyran [2, 3-b] quinoline, new tacrine analogues

A Martínez-Grau, JL Marco - Bioorganic & Medicinal Chemistry Letters, 1997 - Elsevier
The unprecedented Friedländer reaction of densely functionalized 2-amino-3-cyano-4H-
pyrans (1) with cyclohexanone has afforded in one step and good yield 5-amino-4-aryl-3 …

Synthesis, structure, chemical reactivity, and practical significance of 2-amino-4H-pyrans

YM Litvinov, AM Shestopalov - Advances in Heterocyclic Chemistry, 2011 - Elsevier
Publisher Summary The class of 2-amino-4H-pyrans has been known for several decades.
Most of the 2-amino-4H-pyrans are colorless, pale-yellow, or pale-cream crystals with high …

[PDF][PDF] The reactivity of 8-hydroxyquinoline and its derivatives toward α-cyanocinnamonitriles and ethyl α-cyanocinnamates: Synthesis, reactions, and applications of …

M Ahmed, TH Afifib - Heterocycles, 2014 - triggered.edinburgh.clockss.org
The main purpose of this review is to present a literature survey on the reactivity of 8-
hydroxyquinoline and its derivatives toward α-cyanocinnamonitrile or ethyl α …

Arylidenemalononitriles as Versatile Synthons in Heterocyclic Synthesis

P Padmaja, BVS Reddy, VG Ugale… - Current Organic …, 2022 - ingentaconnect.com
Background: Arylidenemalononitriles are valuable synthons for the construction of a variety
of novel complex heterocyclic motifs, fused heterocycle derivatives, and spirocyclic …

Synthesis of some new thiazolo [3, 2-a] pyridines and related heterocyclic systems

MS Al-Thebeiti - Il farmaco, 2000 - Elsevier
New 2, 7-disubstituted 5-amino-6, 8-dicyano-2, 3-dihydro-3-oxo thiazolo [3, 2-a] pyridines
have been prepared. Their cyclization with formamide, nitrous acid and triethylorthoformate …

Ce–Zr/SiO 2: a versatile reusable heterogeneous catalyst for three-component synthesis and solvent free oxidation of benzyl alcohol

R Pagadala, S Maddila, S Rana, SB Jonnalagadda - RSC Advances, 2014 - pubs.rsc.org
Ce–Zr loaded on SiO2 as catalyst provides an extremely efficient method to synthesize
pyranoquinolines. This catalyst is found to be superb for the three-component synthesis of …

Convenient synthesis of amino-substituted pyranopyranones

MZ Piao, K Imafuku - Tetrahedron letters, 1997 - Elsevier
Treatment of kojic acid and triacetic acid lactone with arylmethylenemalononitrile derivatives
in the presence of piperidine in ethanol, respectively, furnished the corresponding amino …

[HTML][HTML] One-pot synthesis of naphthopyranopyrimdine derivatives using nano silica phosphoric acid under thermal and solvent-free conditions

N Yaghmaeiyan, M Mirzaei, A Bamoniri - Results in Chemistry, 2023 - Elsevier
Nano silica phosphoric acid (nano-SPA) as a recoverable solid catalyst was prepared by the
reaction of nano silica chloride with phosphoric acid. The structure of the prepared solid acid …

[PDF][PDF] Synthesis, reactions and antimicrobial activity of 2-amino-4-(8-quinolinol-5-yl)-1-(p-tolyl)-pyrrole-3-carbonitrile

SA Abdel-Mohsen - Bulletin of the Korean Chemical Society, 2005 - Citeseer
A novel 2-amino-4-(8-quinolinol-5-yl)-1-(p-tolyl)-pyrrole-3-cabonitrile (2) was obtained by
the reaction of 2-[2-bromo-1-(8-hydroxyquinolin-5-yl)-ethylidene]-malononitrile (1) with p …

Peculiarities of 2-amino-3-R-4-aryl-4 H-pyranes multicomponent synthesis derived from 1 H-2, 1-benzothiazin-4 (3 H)-one 2, 2-dioxide

DA Lega, NY Gorobets, VP Chernykh, SV Shishkina… - RSC …, 2016 - pubs.rsc.org
The new 2-amino-3-R-4-aryl-6-ethyl-4, 6-dihydropyrano [3, 2-c][2, 1] benzothiazine 5, 5-
dioxides were synthesized via three-component interaction of 1H-2, 1-benzothiazin-4 (3H) …