Ten challenges for clinical translation in psychiatric genetics

EM Derks, JG Thorp, ZF Gerring - Nature Genetics, 2022 - nature.com
Genome-wide association studies have identified hundreds of robust genetic associations
underlying psychiatric disorders and provided important biological insights into disease …

Behavioural genetics methods

EA Willoughby, TJC Polderman… - Nature Reviews Methods …, 2023 - nature.com
The question of why people show individual differences in their behaviours and capacities
has intrigued researchers for centuries. Behaviour genetics offers us various methods to …

Causal inference with genetic data: Past, present, and future

JB Pingault, R Richmond… - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
The set of methods discussed in this collection has emerged from the convergence of two
scientific fields—genetics and causal inference. In this introduction, we discuss relevant …

Triangulating evidence through the inclusion of genetically informed designs

MR Munafò, JPT Higgins… - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Much research effort is invested in attempting to determine causal influences on disease
onset and progression to inform prevention and treatment efforts. However, this is often …

[HTML][HTML] Behaviour genetics and sleep: A narrative review of the last decade of quantitative and molecular genetic research in humans

JJ Madrid-Valero, AM Gregory - Sleep Medicine Reviews, 2023 - Elsevier
During the last decade quantitative and molecular genetic research on sleep has increased
considerably. New behavioural genetics techniques have marked a new era for sleep …

[HTML][HTML] Systematic review and meta-analysis of genetically informed research: associations between parent anxiety and offspring internalizing problems

YI Ahmadzadeh, T Schoeler, M Han, JB Pingault… - Journal of the American …, 2021 - Elsevier
Objective Parent anxiety is associated with offspring internalizing problems (emotional
problems related to anxiety and depression). This may reflect causal processes, whereby …

[HTML][HTML] Exercise and experiments of nature

MJ Joyner, CC Wiggins, SE Baker… - Comprehensive …, 2023 - pmc.ncbi.nlm.nih.gov
In this review we highlight the contributions of passive experiments that address important
exercise related questions in integrative physiology and medicine. Passive experiments …

Causal models and causal modelling in obesity: foundations, methods and evidence

RS Zoh, X Yu, P Dawid, GD Smith… - … of the Royal …, 2023 - royalsocietypublishing.org
Discussing causes in science, if we are to do so in a way that is sensible, begins at the root.
All too often, we jump to discussing specific postulated causes but do not first consider what …

The Co-twin Control Design: implementation and methodological considerations

BMA Gonggrijp, SGA van de Weijer… - Twin Research and …, 2023 - cambridge.org
Establishing causal relationships in observational studies is an important step in research
and policy decision making. The association between an exposure and an outcome can be …

Taking the problem of colliders seriously in the study of crime: A research note

A Novak, BB Boutwell, TB Smith - Journal of Experimental Criminology, 2024 - Springer
Objectives We provide a brief overview of collider bias and its implications for criminological
research. Methods Owing to the nature of the topics studied, as well as the common data …