The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …

Executive dysfunction is the most important predictor for loss of independence in dementia.
As executive function involves the coordination of distributed cerebral functions, executive …

Importance Identifying asymptomatic individuals at high risk of impending cognitive decline
because of Alzheimer disease is crucial for successful prevention of dementia. Vascular risk …

Objective Neuropathological studies have demonstrated that cerebrovascular disease and
Alzheimer disease (AD) pathology frequently co‐occur in older adults. The extent to which …

Objective To determine whether free water (FW) content, initially developed to correct
metrics derived from diffusion tensor imaging and recently found to be strongly associated …

Our goal was to evaluate the utility of diffusion tensor imaging (DTI) for predicting future
cognitive decline in mild cognitive impairment (MCI) in conjunction with Alzheimer's disease …

Noninvasive biomarkers of early neuronal injury may help identify cognitively normal
individuals at risk of developing Alzheimer's disease (AD). A recent diffusion-weighted …

Late-life measures of white matter (WM) microstructural integrity may predict cognitive status,
cognitive decline, and incident mild cognitive impairment (MCI) or dementia. We considered …

Age-related changes in striatal function are potentially important for predicting declining
memory performance over the adult life span. Here, we used fMRI to measure functional …

Healthy lifestyle might alleviate the socioeconomic inequities in health, but the extent of the
joint and interactive effects of these two factors on dementia are unclear. This study aimed to …