Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …

Visualization of cerebral blood flow (CBF) has become an important part of neuroimaging for
a wide range of diseases. Arterial spin labeling (ASL) perfusion magnetic resonance …

With the publication in 2015 of the consensus statement by the perfusion study group of the
International Society for Magnetic Resonance in Medicine (ISMRM) and the EU-COST …

Objective To determine mechanisms underlying regional vulnerability to infarction in sickle
cell disease (SCD) by measuring voxel-wise cerebral blood flow (CBF), oxygen extraction …

Blood transfusions are the mainstay of stroke prevention in pediatric sickle cell anemia
(SCA), but the physiology conferring this benefit is unclear. Cerebral blood flow (CBF) and …

Stroke is common in children with sickle cell disease and results from an imbalance in
oxygen supply and demand. Cerebral blood flow (CBF) is increased in patients with sickle …

Aim Sickle cell disease (SCD) is the commonest cause of childhood stroke worldwide.
Magnetic resonance imaging (MRI) is routinely used to detect additional silent cerebral …

Cerebrovascular reactivity, defined broadly as the ability of brain parenchyma to adjust
cerebral blood flow in response to altered metabolic demand or a vasoactive stimulus, is …

Sickle cell anemia (SCA) is a genetic disease caused by the homozygosity of the HBB: c.
20A> T mutation, which results in the production of hemoglobin S (HbS). In hypoxic …

Background and purpose Silent cerebral infarcts (SCIs) are the most common neurological
complication in children and adults with sickle cell disease (SCD). In this systematic review …