Human leukocyte antigen (HLA) and immune regulation: how do classical and non-classical HLA alleles modulate immune response to human immunodeficiency …
NB Crux, S Elahi - Frontiers in immunology, 2017 - frontiersin.org
The genetic factors associated with susceptibility or resistance to viral infections are likely to
involve a sophisticated array of immune response. These genetic elements may modulate …
involve a sophisticated array of immune response. These genetic elements may modulate …
The unconventional role of HLA-E: The road less traveled
Abstract Histocompatibility Leukocyte Antigens, or HLAs, are one of the most polymorphic
molecules in humans. This high degree of polymorphism endows HLA molecules with the …
molecules in humans. This high degree of polymorphism endows HLA molecules with the …
HLA‐E: Presentation of a Broader Peptide Repertoire Impacts the Cellular Immune Response—Implications on HSCT Outcome
T Kraemer, AA Celik, T Huyton… - Stem cells …, 2015 - Wiley Online Library
The HLA‐E locus encodes a nonclassical class Ib molecule that serves many immune
functions from inhibiting NK cells to activating CTLs. Structural analysis of HLA‐E/NKG2A …
functions from inhibiting NK cells to activating CTLs. Structural analysis of HLA‐E/NKG2A …
The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch
AA Celik, T Kraemer, T Huyton, R Blasczyk… - Immunogenetics, 2016 - Springer
Human leukocyte antigen (HLA)-E molecules are potent inhibitors of NK cell-mediated
killing. Low in polymorphisms, two alleles are widely expressed among diverse populations …
killing. Low in polymorphisms, two alleles are widely expressed among diverse populations …
Clinical and immunological significance of HLA‐E in stem cell transplantation and cancer
L Wieten, NM Mahaweni, CEM Voorter… - Tissue …, 2014 - Wiley Online Library
Human leukocyte antigen‐E (HLA‐E) is a nonclassical HLA class I molecule that canonically
binds peptides derived from the leader sequence of classical HLA class I. HLA‐E can also …
binds peptides derived from the leader sequence of classical HLA class I. HLA‐E can also …
HLA-E: exploiting pathogen-host interactions for vaccine development
Viruses, when used as vectors for vaccine antigen delivery, can induce strong cellular and
humoral responses against target epitopes. Recent work by Hansen et al. describes the use …
humoral responses against target epitopes. Recent work by Hansen et al. describes the use …
DapNet-HLA: adaptive dual-attention mechanism network based on deep learning to predict non-classical HLA binding sites
Y Jing, S Zhang, H Wang - Analytical Biochemistry, 2023 - Elsevier
Human leukocyte antigen (HLA) plays a vital role in immunomodulatory function. Studies
have shown that immunotherapy based on non-classical HLA has essential applications in …
have shown that immunotherapy based on non-classical HLA has essential applications in …
HLA‐E: a novel player for histocompatibility
T Kraemer, R Blasczyk… - Journal of Immunology …, 2014 - Wiley Online Library
The classical class I human leukocyte antigens (HLA‐A,‐B, and‐C) present allele‐specific
self‐or pathogenic peptides originated by intracellular processing to CD8+ immune effector …
self‐or pathogenic peptides originated by intracellular processing to CD8+ immune effector …
HLA‐E allelic genotype correlates with HLA‐E plasma levels and predicts early progression in chronic lymphocytic leukemia
B Wagner, F da Silva Nardi, S Schramm, T Kraemer… - Cancer, 2017 - Wiley Online Library
BACKGROUND Human leukocyte antigen‐E (HLA‐E) is a nonclassical major
histocompatibility complex class I molecule that recently came into sharper focus as a …
histocompatibility complex class I molecule that recently came into sharper focus as a …
HLA-G variability and haplotypes detected by massively parallel sequencing procedures in the geographicaly distinct population samples of Brazil and Cyprus
EC Castelli, P Gerasimou, MA Paz, J Ramalho… - Molecular …, 2017 - Elsevier
The HLA-G molecule presents immunomodulatory properties that might inhibit immune
responses when interacting with specific Natural Killer and T cell receptors, such as …
responses when interacting with specific Natural Killer and T cell receptors, such as …