Recent advances in the developmental origin of neuroblastoma: an overview

M Ponzoni, T Bachetti, MV Corrias, C Brignole… - Journal of Experimental …, 2022 - Springer
Neuroblastoma (NB) is a pediatric tumor that originates from neural crest-derived cells
undergoing a defective differentiation due to genomic and epigenetic impairments …

Skin melanocytes: biology and development

M Cichorek, M Wachulska, A Stasiewicz… - … in Dermatology and …, 2013 - termedia.pl
In the human skin, melanocytes are present in the epidermis and hair follicles. The basic
features of these cells are the ability to melanin production and the origin from neural crest …

Single-cell characterization of malignant phenotypes and developmental trajectories of adrenal neuroblastoma

R Dong, R Yang, Y Zhan, HD Lai, CJ Ye, XY Yao… - Cancer Cell, 2020 - cell.com
Neuroblastoma (NB), which is a subtype of neural-crest-derived malignancy, is the most
common extracranial solid tumor occurring in childhood. Despite extensive research, the …

Hair-bearing human skin generated entirely from pluripotent stem cells

J Lee, CC Rabbani, H Gao, MR Steinhart, BM Woodruff… - Nature, 2020 - nature.com
The skin is a multilayered organ, equipped with appendages (that is, follicles and glands),
that is critical for regulating body temperature and the retention of bodily fluids, guarding …

[HTML][HTML] Tridimensional visualization and analysis of early human development

M Belle, D Godefroy, G Couly, SA Malone, F Collier… - Cell, 2017 - cell.com
Generating a precise cellular and molecular cartography of the human embryo is essential
to our understanding of the mechanisms of organogenesis in normal and pathological …

Neuroblastoma: developmental biology, cancer genomics and immunotherapy

NKV Cheung, MA Dyer - Nature Reviews Cancer, 2013 - nature.com
Neuroblastoma is a solid tumour that arises from the developing sympathetic nervous
system. Over the past decade, our understanding of this disease has advanced …

Single-cell transcriptomic landscape of the developing human spinal cord

J Andersen, N Thom, JL Shadrach, X Chen… - Nature …, 2023 - nature.com
Understanding spinal cord assembly is essential to elucidate how motor behavior is
controlled and how disorders arise. The human spinal cord is exquisitely organized, and this …

Neuroblastoma: molecular pathogenesis and therapy

CU Louis, JM Shohet - Annual review of medicine, 2015 - annualreviews.org
Neuroblastoma is a developmental tumor of young children arising from the embryonic
sympathoadrenal lineage of the neural crest. Neuroblastoma is the primary cause of death …

Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture

J Zhai, Y Xu, H Wan, R Yan, J Guo, R Skory, L Yan… - Cell, 2023 - cell.com
Neural tube (NT) defects arise from abnormal neurulation and result in the most common
birth defects worldwide. Yet, mechanisms of primate neurulation remain largely unknown …

Single-cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human-specific features

T Rayon, RJ Maizels, C Barrington, J Briscoe - Development, 2021 - journals.biologists.com
The spinal cord receives input from peripheral sensory neurons and controls motor output by
regulating muscle innervating motor neurons. These functions are carried out by neural …