Targeted drug delivery—from magic bullet to nanomedicine: principles, challenges, and future perspectives

A Tewabe, A Abate, M Tamrie, A Seyfu… - Journal of …, 2021 - Taylor & Francis
Nanomedicine is an advanced version of Paul Ehrlich's “magic bullet” concept. Targeted
drug delivery is a system of specifying the drug moiety directly into its targeted body area …

Current advances in specialised niosomal drug delivery: Manufacture, characterization and drug delivery applications

BA Witika, KE Bassey, PH Demana… - International journal of …, 2022 - mdpi.com
Development of nanomaterials for drug delivery has received considerable attention due to
their potential for achieving on-target delivery to the diseased area while the surrounding …

Transfersomes as versatile and flexible nano-vesicular carriers in skin cancer therapy: The state of the art

S Rai, V Pandey, G Rai - Nano reviews & experiments, 2017 - Taylor & Francis
Introduction: The skin acts as a barrier and prevents transcutaneous delivery of therapeutic
agents. Transfersomes are novel vesicular systems that are several times more elastic than …

Surfactant effects on lipid-based vesicles properties

R Bnyan, I Khan, T Ehtezazi, I Saleem, S Gordon… - Journal of …, 2018 - Elsevier
Understanding the effect of surfactant properties is critical when designing vesicular delivery
systems. This review evaluates previous studies to explain the influence of surfactant …

Niosomes: a controlled and novel drug delivery system

R Rajera, K Nagpal, SK Singh… - Biological and …, 2011 - jstage.jst.go.jp
During the past decade formulation of vesicles as a tool to improve drug delivery, has
created a lot of interest amongst the scientist working in the area of drug delivery systems …

Therapeutic and cosmeceutical potential of ethosomes: An overview

P Verma, K Pathak - Journal of advanced pharmaceutical …, 2010 - journals.lww.com
The main disadvantage of transdermal drug delivery is the poor penetration of most
compounds into the human skin. The main barrier of the skin is located within its uppermost …

Recent advances and future prospects of phyto-phospholipid complexation technique for improving pharmacokinetic profile of plant actives

J Khan, A Alexander, S Saraf, S Saraf - Journal of controlled release, 2013 - Elsevier
The phyto-phospholipid complexation technique has emerged as one of the leading
methods of improving bioavailability of phytopharmaceuticals having poor competency of …

Drug delivery by soft matter: matrix and vesicular carriers

E Soussan, S Cassel, M Blanzat… - Angewandte Chemie …, 2009 - Wiley Online Library
The increasing need for drug delivery systems that improve specificity and activity and at the
same time reduce toxicity to ensure maximum treatment safety has led to the development of …

Niosomes: a review of their structure, properties, methods of preparation, and medical applications

PL Yeo, CL Lim, SM Chye, APK Ling, RY Koh - Asian Biomedicine, 2017 - sciendo.com
Target-specific drug-delivery systems for the administration of pharmaceutical compounds
enable the localization of drugs to diseased sites. Various types of drug-delivery systems …

Dual-targeting and stimuli-triggered liposomal drug delivery in cancer treatment

N AlSawaftah, WG Pitt, GA Husseini - ACS pharmacology & …, 2021 - ACS Publications
The delivery of chemotherapeutics to solid tumors using smart drug delivery systems
(SDDSs) takes advantage of the unique physiology of tumors (ie, disordered structure, leaky …