[HTML][HTML] Genetic determinants of cardiometabolic and pulmonary phenotypes and obstructive sleep apnoea in HCHS/SOL
Y Zhang, M Elgart, N Kurniansyah, BW Spitzer… - …, 2022 - thelancet.com
Summary Background Obstructive Sleep Apnoea (OSA) often co-occurs with
cardiometabolic and pulmonary diseases. This study is to apply genetic analysis methods to …
cardiometabolic and pulmonary diseases. This study is to apply genetic analysis methods to …
Generalizing polygenic risk scores from Europeans to Hispanics/Latinos
Polygenic risk scores (PRSs) are weighted sums of risk allele counts of single‐nucleotide
polymorphisms (SNPs) associated with a disease or trait. PRSs are typically constructed …
polymorphisms (SNPs) associated with a disease or trait. PRSs are typically constructed …
[HTML][HTML] Metabolomic profiles of sleep-disordered breathing are associated with hypertension and diabetes mellitus development
Sleep-disordered breathing (SDB) is a prevalent disorder characterized by recurrent
episodic upper airway obstruction. Using data from the Hispanic Community Health …
episodic upper airway obstruction. Using data from the Hispanic Community Health …
[HTML][HTML] Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sex
Background Genome-wide association studies (GWAS) for obstructive sleep apnoea (OSA)
are limited due to the underdiagnosis of OSA, leading to misclassification of OSA, which …
are limited due to the underdiagnosis of OSA, leading to misclassification of OSA, which …
Genetics of type 2 diabetes in US Hispanic/Latino individuals: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Few genome-wide association studies (GWAS) of type 2 diabetes (T2D) have been
conducted in US Hispanics/Latinos of diverse backgrounds who are disproportionately …
conducted in US Hispanics/Latinos of diverse backgrounds who are disproportionately …
[HTML][HTML] Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function
Nearly 100 loci have been identified for pulmonary function, almost exclusively in studies of
European ancestry populations. We extend previous research by meta-analyzing genome …
European ancestry populations. We extend previous research by meta-analyzing genome …
[HTML][HTML] Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos
Prior GWAS have identified loci associated with red blood cell (RBC) traits in populations of
European, African, and Asian ancestry. These studies have not included individuals with an …
European, African, and Asian ancestry. These studies have not included individuals with an …
[HTML][HTML] Development and validation of a metabolite index for obstructive sleep apnea across race/ethnicities
Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent episodes of
upper airway obstruction during sleep resulting in oxygen desaturation and sleep …
upper airway obstruction during sleep resulting in oxygen desaturation and sleep …
Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations
Abstract Study Objectives Daytime sleepiness is a consequence of inadequate sleep, sleep–
wake control disorder, or other medical conditions. Population variability in prevalence of …
wake control disorder, or other medical conditions. Population variability in prevalence of …
Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos
D Jain, CJ Hodonsky, UM Schick… - Human molecular …, 2017 - academic.oup.com
Circulating white blood cell (WBC) counts (neutrophils, monocytes, lymphocytes,
eosinophils, basophils) differ by ethnicity. The genetic factors underlying basal WBC traits in …
eosinophils, basophils) differ by ethnicity. The genetic factors underlying basal WBC traits in …