Summary Background Obstructive Sleep Apnoea (OSA) often co-occurs with
cardiometabolic and pulmonary diseases. This study is to apply genetic analysis methods to …

Polygenic risk scores (PRSs) are weighted sums of risk allele counts of single‐nucleotide
polymorphisms (SNPs) associated with a disease or trait. PRSs are typically constructed …

Sleep-disordered breathing (SDB) is a prevalent disorder characterized by recurrent
episodic upper airway obstruction. Using data from the Hispanic Community Health …

Background Genome-wide association studies (GWAS) for obstructive sleep apnoea (OSA)
are limited due to the underdiagnosis of OSA, leading to misclassification of OSA, which …

Few genome-wide association studies (GWAS) of type 2 diabetes (T2D) have been
conducted in US Hispanics/Latinos of diverse backgrounds who are disproportionately …

Nearly 100 loci have been identified for pulmonary function, almost exclusively in studies of
European ancestry populations. We extend previous research by meta-analyzing genome …

Prior GWAS have identified loci associated with red blood cell (RBC) traits in populations of
European, African, and Asian ancestry. These studies have not included individuals with an …

Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent episodes of
upper airway obstruction during sleep resulting in oxygen desaturation and sleep …

Abstract Study Objectives Daytime sleepiness is a consequence of inadequate sleep, sleep–
wake control disorder, or other medical conditions. Population variability in prevalence of …

Circulating white blood cell (WBC) counts (neutrophils, monocytes, lymphocytes,
eosinophils, basophils) differ by ethnicity. The genetic factors underlying basal WBC traits in …