SARS-CoV-2 infection is benign in most individuals but, in around 10% of cases, it triggers
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …

The vast interindividual clinical variability observed in any microbial infection—ranging from
silent infection to lethal disease—is increasingly being explained by human genetic and …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR)
doubles with every 5 y of age from childhood onward. Circulating autoantibodies …

This review serves as an update to the previous Nocardia review by Brown-Elliott et al.
published in 2006 (BA Brown-Elliott, JM Brown, PS Conville, and RJ Wallace. Jr., Clin …

Background Nocardiosis is a rare infection that is often difficult to treat and may be life-
threatening. There is no consensus on its management. Objectives Our aim was to provide …

Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than
classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are …

Nocardia is a ubiquitous environmental pathogen that causes infection primarily following
inhalation into the lungs. It is generally thought to cause infection primarily in …

Anti-cytokine autoantibodies (ACAAs) are increasingly recognized as modulating disease
severity in infection, inflammation and autoimmunity. By reducing or augmenting cytokine …

Pulmonary alveolar proteinosis (PAP) is a diffuse lung disease that results from the
accumulation of lipoproteinaceous material in the alveoli and alveolar macrophages due to …

Background. Nocardiosis is a rare, life-threatening opportunistic infection, affecting 0.04% to
3.5% of patients after solid organ transplant (SOT). The aim of this study was to identify risk …