Towards advances in medicinal plant antimicrobial activity: A review study on challenges and future perspectives

N Vaou, E Stavropoulou, C Voidarou, C Tsigalou… - Microorganisms, 2021 - mdpi.com
The increasing incidence of drug-resistant pathogens raises an urgent need to identify and
isolate new bioactive compounds from medicinal plants using standardized modern …

Review on plant antimicrobials: a mechanistic viewpoint

B Khameneh, M Iranshahy, V Soheili… - … Resistance & Infection …, 2019 - Springer
Microbial resistance to classical antibiotics and its rapid progression have raised serious
concern in the treatment of infectious diseases. Recently, many studies have been directed …

Infection microenvironment-related antibacterial nanotherapeutic strategies

Z Wang, X Liu, Y Duan, Y Huang - Biomaterials, 2022 - Elsevier
The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens

E Peterson, P Kaur - Frontiers in microbiology, 2018 - frontiersin.org
Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

Bacterial resistance to antimicrobial agents

MF Varela, J Stephen, M Lekshmi, M Ojha, N Wenzel… - Antibiotics, 2021 - mdpi.com
Bacterial pathogens as causative agents of infection constitute an alarming concern in the
public health sector. In particular, bacteria with resistance to multiple antimicrobial agents …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

[HTML][HTML] Focus: infectious diseases: vancomycin resistance in Staphylococcus aureus

WA McGuinness, N Malachowa… - The Yale journal of …, 2017 - ncbi.nlm.nih.gov
The evolution of Staphylococcus aureus during the modern antibiotic era has been
delineated by distinct strain emergence events, many of which include acquisition of …

Enzymatic noncovalent synthesis

H He, W Tan, J Guo, M Yi, AN Shy, B Xu - Chemical reviews, 2020 - ACS Publications
Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …

A new antibiotic kills pathogens without detectable resistance

LL Ling, T Schneider, AJ Peoples, AL Spoering… - Nature, 2015 - nature.com
Antibiotic resistance is spreading faster than the introduction of new compounds into clinical
practice, causing a public health crisis. Most antibiotics were produced by screening soil …

Molecular mechanisms of vancomycin resistance

PJ Stogios, A Savchenko - Protein Science, 2020 - Wiley Online Library
Vancomycin and related glycopeptides are drugs of last resort for the treatment of severe
infections caused by Gram‐positive bacteria such as Enterococcus species, Staphylococcus …