An evidence-based systematic review of human knee post-traumatic osteoarthritis (PTOA): timeline of clinical presentation and disease markers, comparison of knee …

CM Khella, R Asgarian, JM Horvath, B Rolauffs… - International Journal of …, 2021 - mdpi.com
Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of
the knee joint is important for diagnosing early disease and developing new and effective …

Current epidemiology and risk factors for the development of hand osteoarthritis

B Plotz, F Bomfim, MA Sohail, J Samuels - Current rheumatology reports, 2021 - Springer
Abstract Purpose of Review Hand osteoarthritis (hand OA), the most common peripheral
arthritis in the world, is less studied than osteoarthritis (OA) of the knee and hip. However, it …

[HTML][HTML] Osteoarthritis biomarkers: year in review

FE Watt - Osteoarthritis and cartilage, 2018 - Elsevier
Objective To summarise important findings from biomarker studies relevant to osteoarthritis
(OA), published between April 2016 and March 2017; to consider these findings in the …

Imaging of osteoarthritis—recent research developments and future perspective

D Hayashi, FW Roemer… - The British journal of …, 2018 - academic.oup.com
In osteoarthritis research, imaging plays an important role in clinical trials and
epidemiological observational studies. In this narrative review article, we will describe recent …

Development and use of biochemical markers in osteoarthritis: current update

AC Bay-Jensen, CS Thudium… - Current opinion in …, 2018 - journals.lww.com
Osteoarthritis is the most common form of joint disease. This presents the osteoarthritis
research community and pharmaceutical companies developing disease-modifying …

[HTML][HTML] Biomarkers of inflammation–LBP and TLR—predict progression of knee osteoarthritis in the DOXY clinical trial

ZY Huang, E Perry, JL Huebner, B Katz, YJ Li… - Osteoarthritis and …, 2018 - Elsevier
Objective To evaluate systemic inflammatory biomarkers in symptomatic knee osteoarthritis
(OA) and their association with radiographic and biochemical OA progression. Methods …

A low cartilage formation and repair endotype predicts radiographic progression of symptomatic knee osteoarthritis

Y Luo, J Samuels, S Krasnokutsky, I Byrjalsen… - Journal of Orthopaedics …, 2021 - Springer
Background Osteoarthritis (OA) is a disease with multiple endotypes. A hallmark of OA is
loss of cartilage; however, it is evident that the rate of cartilage loss differs among patients …

CD44 receptor mediates urate crystal phagocytosis by macrophages and regulates inflammation in a murine peritoneal model of acute gout

E Bousoik, M Qadri, KA Elsaid - Scientific reports, 2020 - nature.com
Gout is a chronic arthritis caused by the deposition of poorly soluble monosodium urate
monohydrate (MSU) crystals in peripheral joints. Resident macrophages initiate …

Urate and osteoarthritis: evidence for a reciprocal relationship

T Neogi, S Krasnokutsky, MH Pillinger - Joint Bone Spine, 2019 - Elsevier
Hyperuricemia is a common condition, and in a subset of patients leads to gout, the most
common inflammatory arthritis. Osteoarthritis is the most common form of arthritis overall …

Exploring the link between uric acid and osteoarthritis

CA Ma, YY Leung - Frontiers in medicine, 2017 - frontiersin.org
Both gout and osteoarthritis (OA) are common forms of arthritis that inflict a huge burden to
an aging population with the increasing prevalence of obesity. Clinicians have long …