The gut microbiota plays a fundamental role in human nutrition and metabolism and may
have direct implications for type 2 diabetes and associated preconditions. An improved …

Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

Dietary pollution by polystyrene microplastics (MPs) can cause hepatic injuries and
microbial dysbiosis. Epigallocatechin-3-gallate (EGCG), the major polyphenol in green tea …

Modifications in the microbiota caused by environmental and genetic reasons can
unbalance the intestinal homeostasis, deregulating the host's metabolism and immune …

Nonalcoholic fatty liver disease (NAFLD) is considered as one of the most prevalent chronic
liver diseases worldwide due to the rapidly rising prevalence of obesity and metabolic …

Gut microbiota is a microecosystem composed of various microorganisms. It plays an
important role in human metabolism, and its metabolites affect different tissues and organs …

The complex interplay between the gut microbiota, the intestinal barrier, the immune system
and the liver is strongly influenced by environmental and genetic factors that can disrupt the …

Non-alcoholic fatty liver disease (NAFLD) represents a global healthcare challenge,
affecting 1 in 4 adults, and death rates are predicted to rise inexorably. The progressive form …

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease, and its
prevalence worldwide is increasing. Several studies support the pathophysiological role of …

Non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease, had no
approved pharmacological agents yet. Obeticholic acid (OCA), a novel bile acid derivative …