Procalcitonin versus C-reactive protein: review of kinetics and performance for diagnosis of neonatal sepsis

S Eschborn, JH Weitkamp - Journal of Perinatology, 2019 - nature.com
Procalcitonin (PCT) and C-reactive protein (CRP) are commonly used biomarkers, but their
diagnostic advantage for neonatal early-onset (EOS) or late-onset (LOS) sepsis is …

The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis: a meta-analysis and systematic …

L Ruan, GY Chen, Z Liu, Y Zhao, GY Xu, SF Li, CN Li… - Critical Care, 2018 - Springer
Background Sepsis is an important cause of neonatal morbidity and mortality; therefore, the
early diagnosis of neonatal sepsis is essential. Method Our aim was to compare the …

Recent advances in biosensors for diagnosis and detection of sepsis: A comprehensive review

S Kumar, S Tripathy, A Jyoti, SG Singh - Biosensors and Bioelectronics, 2019 - Elsevier
Sepsis is one of the leading causes of mortality among critically ill patients globally.
According to WHO report 2018, it is estimated to affect beyond 30 million people worldwide …

Assessment of C-reactive protein diagnostic test accuracy for late-onset infection in newborn infants: a systematic review and meta-analysis

JVE Brown, N Meader, K Wright, J Cleminson… - JAMA …, 2020 - jamanetwork.com
Importance Rapid and accurate diagnosis of late-onset infection in newborn infants could
inform treatment decisions and avoid unnecessary administration of antibiotics. Objective To …

Serum procalcitonin as a diagnostic marker for neonatal sepsis: a systematic review and meta-analysis

EK Vouloumanou, E Plessa… - Intensive care …, 2011 - Springer
Purpose To assess the value of serum procalcitonin (PCT) for the differentiation between
patients with and without neonatal sepsis. Methods We systematically searched PubMed …

Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

G Pontrelli, F De Crescenzo, R Buzzetti… - BMC infectious …, 2017 - Springer
Background A number of biomarkers have been studied for the diagnosis of sepsis in
paediatrics, but no gold standard has been identified. Procalcitonin (PCT) was demonstrated …

Translational research and biomarkers in neonatal sepsis

JR Delanghe, MM Speeckaert - Clinica chimica acta, 2015 - Elsevier
As neonatal sepsis is a severe condition, there is a call for reliable biomarkers to
differentiate between infected and noninfected newborns. Although blood culture has been …

Biomarkers of neonatal sepsis: where we are and where we are going

G Boscarino, R Migliorino, G Carbone, G Davino… - Antibiotics, 2023 - mdpi.com
Neonatal sepsis is a bacterial bloodstream infection leading to severe clinical manifestations
frequently associated with death or irreversible long-term deficits. Antibiotics are the drug of …

[HTML][HTML] Biomarkers for diagnosis of neonatal infections: A systematic analysis of their potential as a point-of-care diagnostics

M Meem, JK Modak, R Mortuza, M Morshed… - Journal of global …, 2011 - ncbi.nlm.nih.gov
Background Neonatal infections annually claim lives of 1.4 million neonates worldwide. Until
now, there is no ideal diagnostic test for detecting sepsis and thus management of possible …

Use of the complete blood cell count in late-onset neonatal sepsis

CP Hornik, DK Benjamin, KC Becker… - The Pediatric …, 2012 - journals.lww.com
Background: Late-onset sepsis is an important cause of morbidity and mortality in infants.
Diagnosis of late-onset sepsis can be challenging. The complete blood cell count and …