ABSTRACT C-Myc overexpression is a common finding in pancreatic cancer and predicts
the aggressive behavior of cancer cells. It binds to the promoter of different genes, thereby …

Abstract High oxidative stress, Th1/Th17 immune response, M1 macrophage inflammation,
and cell death are associated with cardiovascular diseases. Controlled oxidative stress …

Abstract MicroRNA-29 (miR-29) is a critical regulator of fibroinflammatory processes in
human diseases. In this study, we found a decrease in miR-29a in experimental and human …

Small non-coding RNA or microRNA (miRNA) are critical regulators of eukaryotic cells.
Dysregulation of miRNA expression and function has been linked to a variety of diseases …

Cancer is frequently caused by microRNAs, which control post-transcriptional levels of gene
expression by binding to target mRNAs. MiR-29a-3p has recently been shown to play a …

The transdifferentiation from cardiac fibroblasts to myofibroblasts is an important event in the
initiation of cardiac fibrosis. However, the underlying mechanism is not fully understood. Circ …

Lysyl Oxidase Like 2 (LOXL2) belongs to the lysyl oxidase (LOX) family, which comprises
five lysine tyrosylquinone (LTQ)-dependent copper amine oxidases in humans. In 2003 …

An increasing number of studies have demonstrated the significant roles of the interplay
between microenvironmental mechanics in tissues and biochemical-genetic activities in …

LOXL2, a copper-dependent amine oxidase, has emerged as a promising therapeutic target
in hepatocellular carcinoma (HCC). Increased LOXL2 expression in HCC has been linked …

Pancreatic cancer constitutes the fourth most frequent cause of death due to malignancy in
the US. Despite the new therapeutic modalities, the management of pancreatic ductal …