[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

P Guerby, O Tasta, A Swiader, F Pont, E Bujold… - Redox biology, 2021 - Elsevier
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

[HTML][HTML] Oxidative stress: Normal pregnancy versus preeclampsia

DI Chiarello, C Abad, D Rojas, F Toledo… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The role of oxidative stress in the physiopathology of human pregnancy is of particular
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …

Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia

T Cotechini, M Komisarenko, A Sperou… - Journal of Experimental …, 2014 - rupress.org
Fetal growth restriction (FGR) and preeclampsia (PE) are often associated with abnormal
maternal inflammation, deficient spiral artery (SA) remodeling, and altered uteroplacental …

Summary of the NHLBI working group on research on hypertension during pregnancy

JM Roberts, G Pearson, J Cutler, M Lindheimer - Hypertension, 2003 - Am Heart Assoc
A Working Group on Research in Hypertension in Pregnancy was recently convened by the
National Heart, Lung, and Blood Institute to determine the state of knowledge in this area …

[HTML][HTML] Nitric oxide and reactive oxygen species in the pathogenesis of preeclampsia

K Matsubara, T Higaki, Y Matsubara… - International journal of …, 2015 - mdpi.com
Preeclampsia (PE) is characterized by disturbed extravillous trophoblast migration toward
uterine spiral arteries leading to increased uteroplacental vascular resistance and by …

Lead toxicity part II: the role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity.

L Patrick - Alternative medicine review, 2006 - search.ebscohost.com
Lead is an environmentally persistent toxin that causes neurological, hematological,
gastrointestinal, reproductive, circulatory, and immunological pathologies. The propensity for …

Preeclampsia: recent insights

JM Roberts, HS Gammill - Hypertension, 2005 - Am Heart Assoc
Preeclampsia is a pregnancy complication with serious consequences for mother and infant.
The disorder is diagnosed by gestational hypertension and proteinuria but is far more than …

Vitamins C and E to prevent complications of pregnancy-associated hypertension

JM Roberts, L Myatt, CY Spong, EA Thom… - … England Journal of …, 2010 - Mass Medical Soc
Background Oxidative stress has been proposed as a mechanism linking the poor placental
perfusion characteristic of preeclampsia with the clinical manifestations of the disorder. We …

Oxidative stress in the pathogenesis of preeclampsia

CA Hubel - Proceedings of the Society for Experimental …, 1999 - Wiley Online Library
The etiology and pathogenesis of the pregnancy syndrome preeclampsia remain poorly
understood. There is substantial evidence to suggest that the diverse manifestations of …

Molecular mechanisms of maternal vascular dysfunction in preeclampsia

S Goulopoulou, ST Davidge - Trends in molecular medicine, 2015 - cell.com
In preeclampsia, as a heterogeneous syndrome, multiple pathways have been proposed for
both the causal as well as the perpetuating factors leading to maternal vascular dysfunction …