This review begins with a discussion of the large family of Staphylococcus aureus and beta-
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …

Staphylococcus aureus (S. aureus) infections are a major healthcare challenge and new
treatment alternatives are needed. S. aureus septic arthritis, a debilitating joint disease …

Bacterial superantigens (SAg) stimulate T-cell hyper-activation resulting in immune
modulation and severe systemic illnesses such as Staphylococcus aureus toxic shock …

To test the hypothesis that the Staphylococcus aureus enterotoxin gene cluster (egc) can
generate new enterotoxin genes by recombination, we analyzed the egc locus in a broad …

Staphylococcus aureus and Streptococcus pyogenes (group A streptococci) are Gram‐
positive pathogens capable of producing a variety of bacterial exotoxins known as …

Despite knowledge of the effects of toxic shock syndrome (TSS) toxin 1 (TSST-1) on the
adaptive immune system, little is known about stimulation of the innate immune system …

Staphylococcus aureus causes significant illnesses throughout the world, including toxic
shock syndrome (TSS), pneumonia, and infective endocarditis. Major contributors to S …

In the year 2003 there was a 17% increase in the number of publications citing work
performed using optical biosensor technology compared with the previous year. We collated …

Many exotoxins of Gram-positive bacteria, such as superantigens [staphylococcal
enterotoxins, toxic shock syndrome toxin-1 (TSST-1), and streptococcal pyrogenic exotoxins] …

Staphylococcal enterotoxin B (SEB) and related bacterial toxins cause diseases in humans
and laboratory animals ranging from food poisoning, acute lung injury to toxic shock. These …