Functional gastrointestinal disorders (FGIDs) are characterized by chronic complaints
arising from disorganized brain-gut interactions leading to dysmotility and hypersensitivity …

This article examines associations between gluten, polymorphisms of the major
histocompatibility complex, and mucosal pathology representative of the spectrum of gluten …

Mast cells are found resident in tissues throughout the body, particularly in association with
structures such as blood vessels and nerves, and in proximity to surfaces that interface the …

Coeliac disease is a common small bowel enteropathy arising in genetically predisposed
individuals and caused by ingestion of gluten in the diet. Great advances have been made …

Gluten sensitivity is associated with a spectrum of mucosal lesions, arbitrarily termed pre-
infiltrative, infiltrative-hyperplastic, flat-destructive and atrophic-hypoplastic. Histologically …

Previous studies on the frequency of intestinal mast cells and eosinophils in patients with
inflammatory bowel disease yielded conflicting results. In the present morphometric study …

Mast cells (MCs) are currently recognized as effector cells in many settings of the immune
response, including host defense, immune regulation, allergy, chronic inflammation, and …

Chemotactic cytokines related to interleukin‐8 (IL‐8; CXC‐chemokines) or monocyte
chemotactic protein‐1 (MCP‐1; CC‐chemokines) have been shown to stimulate human …

BACKGROUND: The clinical relevance of gastrointestinal food allergy in adults is largely
unknown because the mechanisms are poorly understood and the diagnosis is difficult to …

Background: Menetrier's disease is characterized by giant gastric folds and foveolar
hyperplasia. The extent of mucosal inflammation and glandular atrophy, however, is …