Immunoglobulin A (IgA) plays a key role in defending mucosal surfaces against attack by
infectious microorganisms. Such sites present a major site of susceptibility due to their vast …

Immunoglobulin A (IgA) is the most abundant immunoglobulin synthesized in the human
body. It has the highest concentration in the mucosa and is second only to IgG in serum. IgA …

Protein glycosylation has a huge impact on biological processes in all domains of life. The
type of glycan present on a recombinant glycoprotein depends on protein intrinsic features …

Nicotiana benthamiana is used worldwide as production host for recombinant proteins.
Many recombinant proteins such as monoclonal antibodies, growth factors or viral antigens …

In the past three decades, a great interest has arisen in the use of immunoglobulins as
therapeutic agents. In particular, since the approval of the first monoclonal antibody …

IgA nephropathy (IgAN), the most common primary glomerular disease worldwide, is
characterized by glomerular deposition of IgA1-containing immune complexes. The IgA1 …

Complex carbohydrates (glycans) are the most abundant and versatile biopolymers in
nature. The broad diversity of biochemical functions that carbohydrates cover is a direct …

Background Antibody tests are essential tools to investigate humoral immunity following
SARS-CoV-2 infection or vaccination. While first-generation antibody tests have primarily …

Production of biologics in plants, or plant molecular pharming, is a promising protein
expression technology that is receiving increasing attention from the pharmaceutical …

Immunoglobulin G (IgG) is currently the most studied immunoglobin class and is frequently
used in antibody therapeutics in which its beneficial effector functions are exploited. IgG is …