Histology and immunohistochemistry of thin tissue sections have been the standard
diagnostic procedure in many diseases for decades. This method is highly specific for …

microRNAs are a novel set of small, non-protein-coding nucleotide RNAs that negatively
regulate the expression of target mRNAs. miRNA-21 is a microRNA that is highly enriched in …

Background Brain microvascular endothelial cell (BMEC) injury can affect neuronal survival
by modulating immune responses through the microenvironment. Exosomes are important …

Research studies on the three-dimensional (3D) morphological alterations of the spinal cord
microvasculature after injury provide insight into the pathology of spinal cord injury (SCI) …

Blockage of blood supply while administering chemotherapy to tumors, using trans‐arterial
chemoembolization (TACE), is the most common treatment for intermediate and advanced …

Minimally-invasive monitoring of electrophysiological neural activities in real-time—that
enables quantification of neural functions without a need for invasive craniotomy and the …

The microvasculature plays a key role in oxygen transport in the mammalian brain. Despite
the close coupling between cerebral vascular geometry and local oxygen demand, recent …

The angioarchitecture is a fundamental aspect of brain development and physiology.
However, available imaging tools are unsuited for non-destructive cerebral mapping of the …

There has been increasing interest in using high-resolution micro-tomography to investigate
the morphology of neurovascular networks in the central nervous system, which remain …

Blood vessels are three-dimensional (3D) in structure and precisely connected.
Conventional histological methods are unsuitable for their analysis because of the …