It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …

Vision loss in diabetic retinopathy (DR) is ascribed primarily to retinal vascular abnormalities—
including hyperpermeability, hypoperfusion, and neoangiogenesis—that eventually lead to …

The mouse retina has been used extensively over the past decades to study both
physiologic and pathologic angiogenesis. Over time, various mouse retina models have …

The retina was first described by Herophilus of Chalcedon around 300 bc. It was named by
Rufos of Ephesus (c. 110 ad) and appeared to early anatomists as a surrounding net which …

Diabetic corneal alterations, such as delayed epithelial wound healing, edema, recurrent
erosions, neuropathy/loss of sensitivity, and tear film changes are frequent but …

Neovascular glaucoma (NVG) is a secondary glaucoma generally associated with poor
visual prognosis. The development of new vessels over the iris and the iridocorneal angle …

Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and
one of the major causes of blindness worldwide. The pathogenesis of DR has been …

Long-term diabetes increases the likelihood of developing secondary damage to numerous
systems, and these complications represent a substantial cause of morbidity and mortality …

Diabetic retinopathy continues to be the leading cause of legal blindness among working-
age individuals. The earliest histological features of diabetic retinopathy include neuroretinal …

The glaucomas are neurodegenerative diseases involving death of retinal ganglion cells
and optic nerve head excavation. A major risk factor for this neurodegeneration is a …