Kléber, André G., and Yoram Rudy. Basic Mechanisms of Cardiac Impulse Propagation and
Associated Arrhythmias. Physiol Rev 84: 431–488, 2004; 10.1152/physrev. 00025.2003 …

Gap junctions play a pivotal role for the velocity and the safety of impulse propagation in
cardiac tissue. Under physiologic conditions, the specific subcellular distribution of gap …

Optical techniques have revolutionized the investigation of cardiac cellular physiology and
advanced our understanding of basic mechanisms of electrical activity, calcium …

Generally, impulse propagation in cardiac tissue is assumed to be impaired by a reduction
of intercellular electrical coupling or by the presence of structural discontinuities. Contrary to …

It is traditionally assumed that impulse propagation in cardiac muscle is determined by the
combination of two factors:(1) the active properties of cardiac cell membranes and (2) the …

Conduction in Normal and C× 43+/− Mice. Introduction: Gap junction channels are important
determinants of conduction in the heart and may play a central role in the development of …

The “leading circle model” was the first detailed attempt at understanding the mechanisms of
functional reentry, and remains a widely-used notion in cardiac electrophysiology. The …

Highlights•Postinfarction ventricular tachycardia (VT) caused by a reentrant circuit is an
important clinical problem.•Catheter ablation may not prevent VT because of difficulty in …

Background The long-QT syndrome (LQTS) is an electrophysiological (EP) entity
characterized by prolongation of cardiac repolarization and the occurrence of polymorphic …

Anisotropy, the property of being directionally dependent, is ubiquitous in nature.
Propagation of the electrical impulse in cardiac tissue is anisotropic, a property that is …