[HTML][HTML] The lung microbiome: progress and promise

SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

[HTML][HTML] The lung microbiome during health and disease

K Yagi, GB Huffnagle, NW Lukacs, N Asai - International Journal of …, 2021 - mdpi.com
Healthy human lungs have traditionally been considered to be a sterile organ. However,
culture-independent molecular techniques have reported that large numbers of microbes …

The airway microbiome mediates the interaction between environmental exposure and respiratory health in humans

L Lin, X Yi, H Liu, R Meng, S Li, X Liu, J Yang, Y Xu… - Nature Medicine, 2023 - nature.com
Exposure to environmental pollution influences respiratory health. The role of the airway
microbial ecosystem underlying the interaction of exposure and respiratory health remains …

Pathogenesis of pneumonia and acute lung injury

ME Long, RK Mallampalli, JC Horowitz - Clinical Science, 2022 - portlandpress.com
Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …

[HTML][HTML] Role of Microbiome, Infection, and Inflammation in Autoimmune Diseases

N Amini, M Azimzadeh, MD Dosar, AM Fard… - Kindle, 2023 - preferpub.org
Microorganisms found in the human gastrointestinal tract (GIT) are symbiotic under steady
state conditions and have role in the homeostasis of the human host. The term microbiome …

Metagenomics reveals a core macrolide resistome related to microbiota in chronic respiratory disease

M Mac Aogain, KJX Lau, Z Cai… - American Journal of …, 2020 - atsjournals.org
Rationale: Long-term antibiotic use for managing chronic respiratory disease is increasing;
however, the role of the airway resistome and its relationship to host microbiomes remains …

The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract

O Perdijk, R Azzoni, BJ Marsland - Physiological Reviews, 2024 - journals.physiology.org
The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

[HTML][HTML] Molecular accounting and profiling of human respiratory microbial communities: toward precision medicine by targeting the respiratory microbiome for disease …

AR Alsayed, A Abed, HA Khader… - International Journal of …, 2023 - mdpi.com
The wide diversity of microbiota at the genera and species levels across sites and
individuals is related to various causes and the observed differences between individuals …

Respiratory tract dysbiosis is associated with worse outcomes in mechanically ventilated patients

GD Kitsios, H Yang, L Yang, S Qin, A Fitch… - American journal of …, 2020 - atsjournals.org
Rationale: Host inflammatory responses have been strongly associated with adverse
outcomes in critically ill patients, but the biologic underpinnings of such heterogeneous …

[HTML][HTML] Realising respiratory microbiomic meta-analyses: time for a standardised framework

D Broderick, R Marsh, D Waite, N Pillarisetti, AB Chang… - Microbiome, 2023 - Springer
In microbiome fields of study, meta-analyses have proven to be a valuable tool for identifying
the technical drivers of variation among studies and results of investigations in several …