The extracellular buildup of amyloid beta (Aβ) plaques in the brain is a hallmark of
Alzheimer's disease (AD). Detection of Aβ pathology is essential for AD diagnosis and for …

Discovery and development of clinically useful biomarkers for Alzheimer's disease (AD) and
related dementias have been the focus of recent research efforts. While cerebrospinal fluid …

Alzheimer's disease (AD) is a neurodegenerative disease that causes cognitive impairments
in areas such as memory, language, and reasoning. Currently, a definitive diagnosis of AD …

Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous
condition, arising from diverse microvascular mechanisms. These lead to chronic …

Plasma amyloid-β (Aβ) was associated with brain Aβ deposition and Alzheimer's disease
(AD) development. However, changes of plasma Aβ over the course of cognitive decline in …

Background Identifying risk factors for Alzheimer disease in women is important as women
compose two-thirds of individuals with Alzheimer disease. Previous work links vasomotor …

Objectives The ATN's different modalities (fluids and neuroimaging) for each of the Aβ (A),
tau (T), and neurodegeneration (N) elements are used for the biological diagnosis of …

Background: Single molecule array (SIMOA) and other ultrasensitive detection technologies
have allowed the determination of blood-based biomarkers of Alzheimer's disease (AD) for …

Dementia is a chronic syndrome which is common among the elderly and is associated with
significant morbidity and mortality for patients and their caregivers. Alzheimer's disease …

Accurate differential diagnosis of dementia disorders including Alzheimer disease (AD),
frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), Parkinson disease …