Distinguishing apathy from depression: A review differentiating the behavioral, neuroanatomic, and treatment‐related aspects of apathy from depression in …
Objectives This narrative review describes the clinical features of apathy and depression in
individuals with neurocognitive disorders (NCDs), with the goal of differentiating the two …
individuals with neurocognitive disorders (NCDs), with the goal of differentiating the two …
Protein misfolding and aggregation in the brain: common pathogenetic pathways in neurodegenerative and mental disorders
A Ochneva, Y Zorkina, O Abramova, O Pavlova… - International journal of …, 2022 - mdpi.com
Mental disorders represent common brain diseases characterized by substantial
impairments of social and cognitive functions. The neurobiological causes and mechanisms …
impairments of social and cognitive functions. The neurobiological causes and mechanisms …
Late-life depression is associated with reduced cortical amyloid burden: Findings from the Alzheimer's Disease Neuroimaging Initiative Depression Project
Background We evaluated the role of cortical amyloid deposition as a factor contributing to
memory dysfunction and increased risk of dementia associated with late-life depression …
memory dysfunction and increased risk of dementia associated with late-life depression …
A randomized double-blind placebo-controlled trial of combined escitalopram and memantine for older adults with major depression and subjective memory …
H Lavretsky, KT Laird, B Krause-Sorio… - The American Journal of …, 2020 - Elsevier
Objective Geriatric depression is difficult to treat and frequently accompanied by cognitive
complaints that increase risk for dementia. New treatment strategies targeting both …
complaints that increase risk for dementia. New treatment strategies targeting both …
A transnosographic approach of negative symptoms pathophysiology in schizophrenia and depressive disorders
SB Guessoum, Y Le Strat, C Dubertret… - Progress in Neuro …, 2020 - Elsevier
Abstract Background: Negative Symptoms (blunted affect, alogia, anhedonia, avolition and
asociality) are observed in schizophrenia but also in depressive disorders. Objective: To …
asociality) are observed in schizophrenia but also in depressive disorders. Objective: To …
A complex relationship between suicide, dementia, and amyloid: a narrative review
I Conejero, S Navucet, J Keller, E Olié… - Frontiers in …, 2018 - frontiersin.org
Background: Suicide rates are high among older adults and many conditions have been
related to suicide in this population: chronic illnesses, physical disabilities, cancer, social …
related to suicide in this population: chronic illnesses, physical disabilities, cancer, social …
Regional tau correlates of instrumental activities of daily living and apathy in mild cognitive impairment and Alzheimer's disease dementia
GA Marshall, JR Gatchel, NJ Donovan… - Journal of …, 2019 - content.iospress.com
Background: Instrumental activities of daily living (IADL) impairment and apathy occur in
early-stage Alzheimer's disease (AD) and are associated with regional atrophy and …
early-stage Alzheimer's disease (AD) and are associated with regional atrophy and …
Affective computing for late-life mood and cognitive disorders
Affective computing (also referred to as artificial emotion intelligence or emotion AI) is the
study and development of systems and devices that can recognize, interpret, process, and …
study and development of systems and devices that can recognize, interpret, process, and …
Pharmacologic approaches for the management of apathy in neurodegenerative disorders
Apathy is one of the most frequent behavioral disturbances in many neurodegenerative
disorders and is known to have a negative impact on the disease progression, particularly in …
disorders and is known to have a negative impact on the disease progression, particularly in …
Neuroanatomical abnormalities in older depressed adults with apathy: a systematic review
MA Pimontel, D Kanellopoulos… - Journal of geriatric …, 2020 - journals.sagepub.com
Objective: Apathy is a common phenomenon in late-life depression and is associated with
poor outcomes. Apathy is often unrecognized in older depressed adults, and efficacious …
poor outcomes. Apathy is often unrecognized in older depressed adults, and efficacious …