Highlights•There is an emerging need for new therapies for rare diseases in a shorter time
frame.•Drug repurposing could arise from serendipitous observations or exploiting side …

Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Cancer is increasingly becoming a serious threat to human life and health. Therefore, the
development of safe and effective therapeutic agents against the disease is of crucial …

We are providing an update to our previously published review paper on inhaled
nanoparticles, thus updating with the most recent reports in the literature. The field of …

Erlotinib (ERT), oral administration agents, is one of the most pivotal targeted drugs in the
treatment of nonsmall cell lung cancer (NSCLC); however, its poor solubility, low oral …

Although chimeric antigen receptor T (CAR T) cell immunotherapy has demonstrated
remarkable success in clinical, therapeutic effects are still limited in solid tumor due to lack of …

Sulfobutylether β-cyclodextrin (SBE-β-CD) is a polyanionic cyclic oligosaccharide that
contains glucopyranose units forming a torus ring-like structure. SBE-β-CD is gifted with …

Background: Worldwide, lung cancer is one of the leading causes of cancer death.
Nevertheless, new therapeutic agents have been developed to treat lung cancer that could …

Colloidal nanoparticulate technology has been described in the literature as a versatile drug
delivery system. But it possesses some inherent lacunae in their formulation. Cyclodextrins …

Encompassing a group of complex and heterogeneous diseases, cancer continues to be a
challenge for patients and healthcare systems worldwide. Thus, it is of vital importance to …