Background The dietary consumption of cuprizone–a copper chelator–has long been known
to induce demyelination of specific brain structures and is widely used as model of multiple …

The neurovascular unit (NVU) is composed of vascular cells, glial cells, and neurons. As a
fundamental functional module in the central nervous system, the NVU maintains …

In human demyelinating diseases such as multiple sclerosis (MS), an imbalance between
demyelination and remyelination can trigger progressive degenerative processes. The …

There is a broad consensus that multiple sclerosis (MS) represents more than an
inflammatory disease: it harbors several characteristic aspects of a classical …

Alzheimer's disease (AD) is the most dominant form of dementia characterized by the
deposition of extracellular amyloid plaques and intracellular neurofibrillary tau tangles …

Multiple sclerosis is a neurologic disease caused by immune cell infiltration into the central
nervous system, resulting in gray and white matter inflammation, progressive demyelination …

Introduction: Demyelinating diseases of the central nervous system (CNS) comprise a group
of neurological disorders characterized by progressive (and eventually irreversible) loss of …

Brain computer interfaces (BCIs), including penetrating microelectrode arrays, enable both
recording and stimulation of neural cells. However, device implantation inevitably causes …

Multiple sclerosis (MS) is a chronic inflammatory disease affecting the central nervous
system (CNS). While multiple effective immunomodulatory therapies for MS exist today, they …

Several brain disorders associated with neuroinflammation show sex differences in their
incidence, onset, progression and/or outcome. The different regulation of the …