Classic and new markers in diagnostics and classification of breast cancer

R Beňačka, D Szabóová, Z Guľašová, Z Hertelyová… - Cancers, 2022 - mdpi.com
Simple Summary With ever-increasing incidence, breast cancer is considered a most
diagnosed type of cancer among women worldwide. Breast cancer arises through malignant …

Targeting PI3K/AKT/mTOR pathway in breast cancer: from biology to clinical challenges

K Cerma, F Piacentini, L Moscetti, M Barbolini… - Biomedicines, 2023 - mdpi.com
Breast cancer (BC) is the most common women cancer and cause of cancer death. Despite
decades of scientific progress in BC treatments, the clinical benefit of new drugs is modest in …

MRI-based machine learning radiomics can predict HER2 expression level and pathologic response after neoadjuvant therapy in HER2 overexpressing breast cancer

AGV Bitencourt, P Gibbs, CR Saccarelli, I Daimiel… - …, 2020 - thelancet.com
Background To use clinical and MRI radiomic features coupled with machine learning to
assess HER2 expression level and predict pathologic response (pCR) in HER2 …

A systematic review of the prevalence and diagnostic workup of PIK3CA mutations in HR+/HER2–metastatic breast cancer

EJ Anderson, LE Mollon, JL Dean… - … Journal of Breast …, 2020 - Wiley Online Library
PIK3CA mutation frequency varies among breast cancer (BC) subtypes. Recent evidence
suggests combination therapy with the PI3K inhibitor (PI3Ki) alpelisib and endocrine therapy …

A deep learning image-based intrinsic molecular subtype classifier of breast tumors reveals tumor heterogeneity that may affect survival

MI Jaber, B Song, C Taylor, CJ Vaske, SC Benz… - Breast Cancer …, 2020 - Springer
Background Breast cancer intrinsic molecular subtype (IMS) as classified by the expression-
based PAM50 assay is considered a strong prognostic feature, even when controlled for by …

Deep learning radiomics model based on breast ultrasound video to predict HER2 expression status

MY Quan, YX Huang, CY Wang, Q Zhang… - Frontiers in …, 2023 - frontiersin.org
Purpose The detection of human epidermal growth factor receptor 2 (HER2) expression
status is essential to determining the chemotherapy regimen for breast cancer patients and …

Identifying methylation pattern and genes associated with breast cancer subtypes

L Chen, T Zeng, X Pan, YH Zhang, T Huang… - International journal of …, 2019 - mdpi.com
Breast cancer is regarded worldwide as a severe human disease. Various genetic
variations, including hereditary and somatic mutations, contribute to the initiation and …

[HTML][HTML] Molecular testing in breast cancer: Current status and future directions

L Sun, A Wu, GR Bean, IS Hagemann, CY Lin - The Journal of Molecular …, 2021 - Elsevier
Molecular testing in breast cancer is a rapidly developing field that is becoming increasingly
integral to patient care. This article provides an overview of currently available molecular …

miRNA Expression Profiling in Human Breast Cancer Diagnostics and Therapy

I Dziechciowska, M Dąbrowska, A Mizielska… - Current Issues in …, 2023 - mdpi.com
Breast cancer is one of the most commonly diagnosed cancer types worldwide. Regarding
molecular characteristics and classification, it is a heterogeneous disease, which makes it …

Pathological diagnosis, work-up and reporting of breast cancer 1st central-eastern european professional consensus statement on breast cancer

G Cserni, M Francz, B Járay, E Kálmán… - Pathology and …, 2022 - por-journal.com
This text is based on the recommendations accepted by the 4th Hungarian Consensus
Conference on Breast Cancer, modified on the basis of the international consultation and …