Toxoplasma Effectors Targeting Host Signaling and Transcription
Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …
The interplay between toxoplasmosis and host miRNAs: Mechanisms and consequences
Toxoplasmosis is one of the highly prevalent zoonotic diseases worldwide caused by the
parasite Toxoplasma gondii (T. gondii). The infection with T. gondii could pass unidentified …
parasite Toxoplasma gondii (T. gondii). The infection with T. gondii could pass unidentified …
Lessons from Toxoplasma: Host responses that mediate parasite control and the microbial effectors that subvert them
EM Frickel, CA Hunter - Journal of Experimental Medicine, 2021 - rupress.org
The intracellular parasite Toxoplasma gondii has long provided a tractable experimental
system to investigate how the immune system deals with intracellular infections. This review …
system to investigate how the immune system deals with intracellular infections. This review …
Dual transcriptional profiling of mice and Toxoplasma gondii during acute and chronic infection
Background The obligate intracellular parasite Toxoplasma gondii establishes a life-long
chronic infection within any warm-blooded host. After ingestion of an encysted parasite, T …
chronic infection within any warm-blooded host. After ingestion of an encysted parasite, T …
The clinical application of microRNAs in infectious disease
RE Drury, D O'Connor, AJ Pollard - Frontiers in immunology, 2017 - frontiersin.org
MicroRNAs (miRNAs) are short single-stranded non-coding RNA sequences that
posttranscriptionally regulate up to 60% of protein encoding genes. Evidence is emerging …
posttranscriptionally regulate up to 60% of protein encoding genes. Evidence is emerging …
MicroRNAs: biological regulators in pathogen–host interactions
SM Acuna, LM Floeter-Winter, SM Muxel - Cells, 2020 - mdpi.com
An inflammatory response is essential for combating invading pathogens. Several effector
components, as well as immune cell populations, are involved in mounting an immune …
components, as well as immune cell populations, are involved in mounting an immune …
Pathogenic infection in male mice changes sperm small RNA profiles and transgenerationally alters offspring behavior
Germline epigenetic factors influence transgenerational inheritance of behavioral traits upon
changes in experience and environment. Immune activation due to infection can also …
changes in experience and environment. Immune activation due to infection can also …
Gut microbes and host behavior: the forgotten members of the gut-microbiome
A Weiner, S Turjeman, O Koren - Neuropharmacology, 2023 - Elsevier
The gut microbiota refers to an entire population of microorganisms that colonize the gut.
This community includes viruses, prokaryotes (bacteria and archaea), and eukaryotes (fungi …
This community includes viruses, prokaryotes (bacteria and archaea), and eukaryotes (fungi …
Toxoplasma gondii: CD8 T Cells Cry for CD4 Help
IA Khan, SJ Hwang, M Moretto - Frontiers in cellular and infection …, 2019 - frontiersin.org
Toxoplasma gondii, an apicomplexan parasite, is a pathogenic protozoan that can infect the
central nervous system. In pregnant women, infection can result in congenital problems of …
central nervous system. In pregnant women, infection can result in congenital problems of …
Human microRNAs in host–parasite interaction: a review
MicroRNAs (miRNAs) are a group of small noncoding RNA molecules with significant
capacity to regulate the gene expression at the post-transcriptional level in a sequence …
capacity to regulate the gene expression at the post-transcriptional level in a sequence …