Advances and recent trends in the field of monolithic columns for chromatography

F Svec, Y Lv - Analytical chemistry, 2015 - ACS Publications
This review summarizes developments in the field of monolithic columns for
chromatographic applications that mostly appeared during the last 2 or so years and that we …

Challenges and advances in the fabrication of monolithic bioseparation materials and their applications in proteomics research

S Ma, Y Li, C Ma, Y Wang, J Ou, M Ye - Advanced Materials, 2019 - Wiley Online Library
High‐performance liquid chromatography integrated with tandem mass spectrometry (HPLC–
MS/MS) has become a powerful technique for proteomics research. Its performance heavily …

Core–shell, ultrasmall particles, monoliths, and other support materials in high-performance liquid chromatography

N Tanaka, DV McCalley - Analytical chemistry, 2016 - ACS Publications
(HPLC) over the last 10 years or so since the commercial introduction of smaller sub-2 μm
particle columns. 1 These particles offer particular advantages in terms of increasing the …

Porous polymer monoliths: From their fundamental structure to analytical engineering applications

I Nischang, TJ Causon - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
The primary need for advanced porous materials with well-understood and enhanced
properties is identified for implementations in the fields of life science and engineering. The …

Current trends in the development of porous polymer monoliths for the separation of small molecules

J Urban - Journal of separation science, 2016 - Wiley Online Library
Since their introduction, the main application area of porous polymer monoliths has been in
the fast gradient separation of synthetic and natural polymers. On the other hand, it has …

Click polymerization for preparation of monolithic columns for liquid chromatography

Z Liu, J Ou, H Zou - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
In recent years, polymerizations based on click reactions (thiol-ene, thiol-yne, thiol-Michael,
thiol-epoxy and amine-epoxy) have been utilized to prepare monolithic columns. These …

Chromatographic separation of peptides and proteins for characterization of proteomes

Y Liang, L Zhang, Y Zhang - Chemical Communications, 2023 - pubs.rsc.org
Characterization of proteomes aims to comprehensively characterize proteins in cells or
tissues via two main strategies:(1) bottom-up strategy based on the separation and …

Utilizing RAFT polymerization for the preparation of well-defined bicontinuous porous polymeric supports: application to liquid chromatography separation of …

A Khodabandeh, RD Arrua, SC Thickett… - ACS Applied Materials …, 2021 - ACS Publications
Polymer-based monolithic high-performance liquid chromatography (HPLC) columns are
normally obtained by conventional free-radical polymerization. Despite being …

Synthesis of porous polymers by means of Michael addition reaction of multifunctional acetoacetate and poly (ethylene glycol) diacrylate

N Naga, M Satoh, T Magara, K Ahmed… - European Polymer …, 2022 - Elsevier
Michael-addition reaction between multifunctional-acetoacetate, meso-erythritol tetra-
acetoacetate (ETAA) or d-sorbitol hexa-acetoacetate (SHAA), and poly (ethylene glycol) …

Guidelines for tuning the macropore structure of monolithic columns for high‐performance liquid chromatography

JL Dores‐Sousa… - Journal of separation …, 2019 - Wiley Online Library
The ability to control the external porosity and to tune the dimensions of the macropore size
on multiple length scales provides the possibility of tailoring the monolithic support structure …