Inhibitory stabilization and cortical computation

S Sadeh, C Clopath - Nature Reviews Neuroscience, 2021 - nature.com
Neuronal networks with strong recurrent connectivity provide the brain with a powerful
means to perform complex computational tasks. However, high-gain excitatory networks are …

[HTML][HTML] Regulation of circuit organization and function through inhibitory synaptic plasticity

YK Wu, C Miehl, J Gjorgjieva - Trends in Neurosciences, 2022 - cell.com
Diverse inhibitory neurons in the mammalian brain shape circuit connectivity and dynamics
through mechanisms of synaptic plasticity. Inhibitory plasticity can establish …

An increase of inhibition drives the developmental decorrelation of neural activity

M Chini, T Pfeffer, I Hanganu-Opatz - Elife, 2022 - elifesciences.org
Throughout development, the brain transits from early highly synchronous activity patterns to
a mature state with sparse and decorrelated neural activity, yet the mechanisms underlying …

[HTML][HTML] How many neurons are sufficient for perception of cortical activity?

HWP Dalgleish, LE Russell, AM Packer, A Roth… - Elife, 2020 - elifesciences.org
Many theories of brain function propose that activity in sparse subsets of neurons underlies
perception and action. To place a lower bound on the amount of neural activity that can be …

[HTML][HTML] Spatiotemporal constraints on optogenetic inactivation in cortical circuits

N Li, S Chen, ZV Guo, H Chen, Y Huo, HK Inagaki… - Elife, 2019 - elifesciences.org
Optogenetics allows manipulations of genetically and spatially defined neuronal populations
with excellent temporal control. However, neurons are coupled with other neurons over …

[HTML][HTML] A disinhibitory circuit for contextual modulation in primary visual cortex

AJ Keller, M Dipoppa, MM Roth, MS Caudill, A Ingrosso… - Neuron, 2020 - cell.com
Context guides perception by influencing stimulus saliency. Accordingly, in visual cortex,
responses to a stimulus are modulated by context, the visual scene surrounding the …

[HTML][HTML] VIP interneurons in mouse primary visual cortex selectively enhance responses to weak but specific stimuli

DJ Millman, GK Ocker, S Caldejon, I Kato, JD Larkin… - Elife, 2020 - elifesciences.org
Vasoactive intestinal peptide-expressing (VIP) interneurons in the cortex regulate feedback
inhibition of pyramidal neurons through suppression of somatostatin-expressing (SST) …

[HTML][HTML] What is the dynamical regime of cerebral cortex?

Y Ahmadian, KD Miller - Neuron, 2021 - cell.com
Many studies have shown that the excitation and inhibition received by cortical neurons
remain roughly balanced across many conditions. A key question for understanding the …

[HTML][HTML] Optimal anticipatory control as a theory of motor preparation: A thalamo-cortical circuit model

TC Kao, MS Sadabadi, G Hennequin - Neuron, 2021 - cell.com
Across a range of motor and cognitive tasks, cortical activity can be accurately described by
low-dimensional dynamics unfolding from specific initial conditions on every trial. These" …

[HTML][HTML] Transcranial electrical stimulation: How can a simple conductor orchestrate complex brain activity?

MR Krause, PG Vieira, CC Pack - Plos Biology, 2023 - journals.plos.org
Transcranial electrical stimulation (tES) is one of the oldest and yet least understood forms of
brain stimulation. The idea that a weak electrical stimulus, applied outside the head, can …