Introduction Neuroendocrine neoplasms (NEN) are heterogeneous malignancies that can
arise at almost any anatomical site and are classified as biologically distinct well …

Simple Summary Neuroendocrine neoplasms are divided into two groups: well-
differentiated neuroendocrine tumors and poorly differentiated neuroendocrine carcinomas …

Neuroendocrine neoplasms (NENs) comprise well-differentiated neuroendocrine tumors
(NETs) and poorly differentiated neuroendocrine carcinomas (NECs). Treatment options for …

Neuroendocrine neoplasms (NENs) can develop in almost any organ and span a spectrum
from well-differentiated and indolent neuroendocrine tumours (NETs) to poorly differentiated …

Molecular abnormalities that shape human neoplasms dissociate their phenotypic
landscape from that of the healthy counterpart. Through the lens of a microscope, tumour …

Corticotroph macroadenomas are rare but difficult to manage intracranial neoplasms.
Mutations in the two Cushing's disease mutational hotspots USP8 and USP48 are less …

Background Neuroendocrine carcinomas of the gastrointestinal tract (GI‐NECs) remain a
disease of grim prognosis with limited therapeutic options. Their molecular characteristics …

Midgut neuroendocrine neoplasms (NENs) are one of the most common subtypes of NEN,
and their incidence is rising globally. Despite being the most frequently diagnosed …

During the course of pancreatic neuroendocrine tumors (NETs), they generally become
more heterogeneous with individual cells exhibiting distinct molecular fingerprints. This …

Pancreatic neuroendocrine tumors (PanNET) are a group of rare sporadic malignant tumors
in the pancreas. MEN1 is the most frequently mutated gene in PanNETs. The MEN1 …