Engineering C4 photosynthesis into C3 chassis in the synthetic biology age

ML Schuler, O Mantegazza, APM Weber - The Plant Journal, 2016 - Wiley Online Library
C4 photosynthetic plants outperform C3 plants in hot and arid climates. By concentrating
carbon dioxide around Rubisco C4 plants drastically reduce photorespiration. The …

[HTML][HTML] Tools and principles for microbial gene circuit engineering

RW Bradley, M Buck, B Wang - Journal of Molecular Biology, 2016 - Elsevier
Synthetic biologists aim to construct novel genetic circuits with useful applications through
rational design and forward engineering. Given the complexity of signal processing that …

[HTML][HTML] A genome-wide association study of wheat spike related traits in China

J Liu, Z Xu, X Fan, Q Zhou, J Cao, F Wang… - Frontiers in plant …, 2018 - frontiersin.org
Rapid detection of allelic variation and identification of advantage haplotypes responsible
for spike related traits play a crucial role in wheat yield improvement. The released genome …

Synthetic Biology─ High time to deliver?

AD Hanson, V Lorenzo - ACS synthetic biology, 2023 - ACS Publications
Synthetic biology (SynBio) has attracted like no other recent development the attention not
only of Life Science researchers and engineers but also of intellectuals, technology think …

The number of catalytic cycles in an enzyme's lifetime and why it matters to metabolic engineering

AD Hanson, DR McCarty, CS Henry… - Proceedings of the …, 2021 - National Acad Sciences
Metabolic engineering uses enzymes as parts to build biosystems for specified tasks.
Although a part's working life and failure modes are key engineering performance indicators …

Multidimensional approaches for studying plant defence against insects: from ecology to omics and synthetic biology

P Barah, AM Bones - Journal of Experimental Botany, 2015 - academic.oup.com
The biggest challenge for modern biology is to integrate multidisciplinary approaches
towards understanding the organizational and functional complexity of biological systems at …

Engineering therapeutic T cells: from synthetic biology to clinical trials

JH Esensten, JA Bluestone… - Annual Review of …, 2017 - annualreviews.org
Engineered T cells are currently in clinical trials to treat patients with cancer, solid organ
transplants, and autoimmune diseases. However, the field is still in its infancy. The design …

[HTML][HTML] Adapting enzymes to improve their functionality in plants: why and how

ER Oliveira-Filho, C Voiniciuc… - Biochemical Society …, 2023 - portlandpress.com
Synthetic biology creates new metabolic processes and improves existing ones using
engineered or natural enzymes. These enzymes are often sourced from cells that differ from …

Genomes by design

AD Haimovich, P Muir, FJ Isaacs - Nature Reviews Genetics, 2015 - nature.com
Next-generation DNA sequencing has revealed the complete genome sequences of
numerous organisms, establishing a fundamental and growing understanding of genetic …

A generalized computational framework to streamline thermodynamics and kinetics analysis of metabolic pathways

C Wu, H Jiang, I Kalra, X Wang, M Cano… - Metabolic …, 2020 - Elsevier
Metabolic engineering is a critical biotechnological approach in addressing global energy
and environment challenges. Most engineering efforts, however, consist of laborious and …