The emerging mechanisms and functions of microautophagy

L Wang, DJ Klionsky, HM Shen - Nature reviews Molecular cell biology, 2023 - nature.com
Abstract 'Autophagy'refers to an evolutionarily conserved process through which cellular
contents, such as damaged organelles and protein aggregates, are delivered to lysosomes …

To degrade or not to degrade: mechanisms and significance of endocytic recycling

PJ Cullen, F Steinberg - Nature reviews Molecular cell biology, 2018 - nature.com
Newly endocytosed integral cell surface proteins are typically either directed for degradation
or subjected to recycling back to the plasma membrane. The sorting of integral cell surface …

Principles of ubiquitin-dependent signaling

E Oh, D Akopian, M Rape - Annual review of cell and …, 2018 - annualreviews.org
Ubiquitylation is an essential posttranslational modification that controls cell division,
differentiation, and survival in all eukaryotes. By combining multiple E3 ligases (writers) …

The enigmatic endosome–sorting the ins and outs of endocytic trafficking

N Naslavsky, S Caplan - Journal of cell science, 2018 - journals.biologists.com
The early endosome (EE), also known as the sorting endosome (SE) is a crucial station for
the sorting of cargoes, such as receptors and lipids, through the endocytic pathways. The …

[HTML][HTML] Targeted therapy using engineered extracellular vesicles: principles and strategies for membrane modification

Q Liu, D Li, X Pan, Y Liang - Journal of nanobiotechnology, 2023 - Springer
Abstract Extracellular vesicles (EVs) are 30–150 nm membrane-bound vesicles naturally
secreted by cells and play important roles in intercellular communication by delivering …

Biogenesis, membrane trafficking, functions, and next generation nanotherapeutics medicine of extracellular vesicles

S Gurunathan, MH Kang, M Qasim… - International Journal of …, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous group of membrane-limited vesicles and
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …

Structures, functions, and dynamics of ESCRT-III/Vps4 membrane remodeling and fission complexes

J McCullough, A Frost… - Annual review of cell and …, 2018 - annualreviews.org
The endosomal sorting complexes required for transport (ESCRT) pathway mediates
cellular membrane remodeling and fission reactions. The pathway comprises five core …

[HTML][HTML] Cell entry and release of quasi-enveloped human hepatitis viruses

A Das, EE Rivera-Serrano, X Yin, CM Walker… - Nature Reviews …, 2023 - nature.com
Infectious hepatitis type A and type E are caused by phylogenetically distinct single-
stranded, positive-sense RNA viruses that were once considered to be non-enveloped …

[HTML][HTML] Extracellular vesicles as delivery vehicles of specific cellular cargo

B Mir, C Goettsch - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs) mediate cell-to-cell communication via the transfer of
biomolecules locally and systemically between organs. It has been elucidated that the …

[HTML][HTML] Extracellular vesicle-and extracellular vesicle mimetics-based drug delivery systems: new perspectives, challenges, and clinical developments

P Gangadaran, BC Ahn - Pharmaceutics, 2020 - mdpi.com
Extracellular vesicles (EVs) are small membrane-based nanovesicles naturally released
from cells. Extracellular vesicles mimetics (EVMs) are artificial vesicles engineered from …