[HTML][HTML] Review on Cerebral Malaria-Pathogenesis and Role of EphA2 Receptor in Maintaining Blood Brain Barrier Integrity

MS Shaikh, MS Baig, SS Ali, A Ahmad… - Health Sciences …, 2024 - Elsevier
Plasmodium species causes cerebral malaria (CM), a dangerous parasitic illness. The
World Health Organization estimates that there were roughly 228 million cases of malaria in …

Drug discovery: In silico dry data can bypass biological wet data?

M Tognolini, A Lodola, C Giorgio - British Journal of …, 2024 - Wiley Online Library
The recent and extraordinary increase in computer power, along with the availability of
efficient algorithms based on artificial intelligence, has prompted a large number of …

Targeting host tyrosine kinase receptor EphA2 signaling via small-molecule ALW-II-41-27 inhibits macrophage pro-inflammatory signaling responses to Pneumocystis …

TJ Kottom, EM Carmona, AH Limper - Antimicrobial Agents and …, 2024 - Am Soc Microbiol
Pneumocystis jirovecii, the fungus that causes Pneumocystis jirovecii pneumonia (PJP), is a
leading cause of morbidity and mortality in immunocompromised individuals. We have …

Efficacy of Albizia malacophylla (A. Rich.) Walp.(Leguminosae) methanol (80%) leaf extract and solvent fractions against Plasmodium berghei-induced malaria in …

G Tadege, A Dagne, GK Bizuneh, D Abebe… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Novel drugs are needed to address the issue of malarial
infection resistance; natural items can be a different source of these medications. Albizia …

A rapid and large volume synthesis of mono-, di-, tri-, and tetra-substituted imidazole derivatives via ultrasonic radiation-driven technique

MS Shaikh, MA Kale, M Zehravi, A Unnisa… - Radiation Effects and …, 2024 - Taylor & Francis
Sonochemistry under controlled conditions has proven effective in medicinal chemistry and
drug development. It can substantially shorten reaction timelines from days or hours to …