The group A streptococci are associated with a group of diseases affecting the heart, brain,
and joints that are collectively referred to as acute rheumatic fever. The streptococcal …

Rheumatic heart valve disease (RHVD) is a post-infectious sequel of acute rheumatic fever
resulting from an abnormal immune response to a streptococcal pharyngitis that triggers …

Streptococcus pyogenes, also known as group A streptococcus (StrepA), is a bacterium that
causes a range of human diseases, including pharyngitis, impetigo, invasive infections, and …

Nearly a century after rheumatic fever (RF) and rheumatic heart disease (RHD) was
eradicated from the developed world, the disease remains endemic in many low-and middle …

Rheumatic heart disease (RHD) remains a major cause of preventable death and disability
in children and young adults. Despite significant advances in medical technology and …

We have developed a candidate vaccine to protect against multiple strains of Streptococcus
pyogenes infections. The candidate vaccine contains two synthetic peptides derived from S …

Dopamine receptor autoantibody signaling in infectious sequelae differentiates movement
vs neuropsychiatric disorders Chandra M. Page 1 Dopamine receptor autoantibody …

Group A streptococcal (GAS) infection is associated with a spectrum of autoimmune
diseases including acute rheumatic fever/rheumatic heart disease (ARF/RHD) and …

Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described
as autoimmune sequelae of Streptococcus pyogenes or group A streptococcal (GAS) …

The pathogenesis of Acute Rheumatic Fever/Rheumatic Heart Disease (ARF/RHD) and
associated neurobehavioral complications including Sydenham's chorea (SC) is complex …