[HTML][HTML] The hypothalamic-pituitary-adrenal axis: development, programming actions of hormones, and maternal-fetal interactions

JA Sheng, NJ Bales, SA Myers, AI Bautista… - Frontiers in behavioral …, 2021 - frontiersin.org
The hypothalamic-pituitary adrenal axis is a complex system of neuroendocrine pathways
and feedback loops that function to maintain physiological homeostasis. Abnormal …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Hypothalamic–pituitary–adrenal and hypothalamic–pituitary–gonadal axes: sex differences in regulation of stress responsivity

MG Oyola, RJ Handa - stress, 2017 - Taylor & Francis
Gonadal hormones play a key role in the establishment, activation, and regulation of the
hypothalamic–pituitary–adrenal (HPA) axis. By influencing the response and sensitivity to …

[HTML][HTML] Social brain, social dysfunction and social withdrawal

S Porcelli, N Van Der Wee, S van der Werff… - Neuroscience & …, 2019 - Elsevier
The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

The neural mechanisms and circuitry of the pair bond

H Walum, LJ Young - Nature Reviews Neuroscience, 2018 - nature.com
Love is one of our most powerful emotions, inspiring some of the greatest art, literature and
conquests of human history. Although aspects of love are surely unique to our species …

Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala

CA Marcinkiewcz, CM Mazzone, G D'Agostino… - Nature, 2016 - nature.com
Serotonin (also known as 5-hydroxytryptamine (5-HT)) is a neurotransmitter that has an
essential role in the regulation of emotion. However, the precise circuits have not yet been …

The neuroendocrinology of social isolation

JT Cacioppo, S Cacioppo, JP Capitanio… - Annual review of …, 2015 - annualreviews.org
Social isolation has been recognized as a major risk factor for morbidity and mortality in
humans for more than a quarter of a century. Although the focus of research has been on …

Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors

ID Neumann, R Landgraf - Trends in neurosciences, 2012 - cell.com
Oxytocin and vasopressin are regulators of anxiety, stress-coping, and sociality. They are
released within hypothalamic and limbic areas from dendrites, axons, and perikarya …

Psychobiological mechanisms underlying the social buffering of the hypothalamic–pituitary–adrenocortical axis: A review of animal models and human studies across …

CE Hostinar, RM Sullivan, MR Gunnar - Psychological bulletin, 2014 - psycnet.apa.org
Discovering the stress-buffering effects of social relationships has been one of the major
findings in psychobiology in the last century. However, an understanding of the underlying …

Diverging neural pathways assemble a behavioural state from separable features in anxiety

SY Kim, A Adhikari, SY Lee, JH Marshel, CK Kim… - Nature, 2013 - nature.com
Behavioural states in mammals, such as the anxious state, are characterized by several
features that are coordinately regulated by diverse nervous system outputs, ranging from …