Identification and validation of key genes with prognostic value in non‐small‐cell lung cancer via integrated bioinformatics analysis

L Wang, J Qu, Y Liang, D Zhao, FUL Rehman… - Thoracic …, 2020 - Wiley Online Library
Background Lung cancer is the most common cause of cancer‐related death among all
human cancers and the five‐year survival rates are only 23%. The precise molecular …

Suppressive effects of umbilical cord mesenchymal stem cell-derived exosomal miR-15a-5p on the progression of cholangiocarcinoma by inhibiting CHEK1 …

N Li, B Wang - Cell death discovery, 2022 - nature.com
Currently, surgical extraction is the main therapy for cholangiocarcinoma (CCA) patients, but
it's highly susceptible to postsurgical complications and recurrence rate. Thus, we identified …

Exploration of predictive and prognostic alternative splicing signatures in lung adenocarcinoma using machine learning methods

Q Cai, B He, P Zhang, Z Zhao, X Peng, Y Zhang… - Journal of Translational …, 2020 - Springer
Background Alternative splicing (AS) plays critical roles in generating protein diversity and
complexity. Dysregulation of AS underlies the initiation and progression of tumors. Machine …

[HTML][HTML] Survival analysis of cancer patients in north eastern Nigeria from 2004–2017–a Kaplan-Meier method

PI Adamu, MO Adamu, HI Okagbue… - … Journal of Medical …, 2019 - ncbi.nlm.nih.gov
BACKGROUND: Cancer is a deadly malignant disease and is prevalent in Sub Saharan
Africa. The North East part of Nigeria in particular and the country, in general, are struggling …

Analysis of serum peptidome profiles of non-metastatic and metastatic feline mammary carcinoma using liquid chromatography-tandem mass spectrometry

W Paphussaro, S Roytrakul, N Phaonakrop… - BMC Veterinary …, 2024 - Springer
Background Feline mammary carcinoma (FMC) is a common aggressive and highly
metastatic cancer affecting female cats. Early detection is essential for preventing local and …

[Retracted] Biomarkers for Breast Adenocarcinoma Using In Silico Approaches

J Pandi, A Arulprakasam, R Dhandapani… - Evidence‐Based …, 2022 - Wiley Online Library
This work elucidates the idea of finding probable critical genes linked to breast
adenocarcinoma. In this study, the GEO database gene expression profile data set …

[HTML][HTML] Lung Cancer in Nigeria

KE Okonta, LA Baiyewu, MA Jimoh - Journal of Thoracic Oncology, 2023 - Elsevier
Nigeria, a tropical and sub-Saharan African nation, is located in the Western African region
sharing its southern border with the Atlantic Ocean by the Gulf of Guinea. 1, 2 It is …

[HTML][HTML] Comprehensive analysis of candidate diagnostic and prognostic biomarkers associated with lung adenocarcinoma

J Li, X Liu, Z Cui, G Han - Medical Science Monitor: International …, 2020 - ncbi.nlm.nih.gov
Comprehensive Analysis of Candidate Diagnostic and Prognostic Biomarkers Associated with
Lung Adenocarcinoma - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Identification of Key Biomarkers and Pathways in Small‐Cell Lung Cancer Using Biological Analysis

H Liu, T Li, X Ye, J Lyu - BioMed Research International, 2021 - Wiley Online Library
Background. Small‐cell lung cancer (SCLC) is a major cause of carcinoma‐related deaths
worldwide. The aim of this study was to identify the key biomarkers and pathways in SCLC …

Computational design of Checkpoint Kinase-1 (CHK-1) inhibitors for cancer therapy

J Chandrasekaran, S Kanekar, S Dagamajalu, P Modi… - 2023 - researchsquare.com
CHK-1 kinase belongs to the serine/threonine family of kinases, which play a vital role in cell
cycle arrest and proved to be a promising therapeutic target to control cancer development …