Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

The blood brain barrier (BBB) presents a formidable challenge to the delivery of drugs into
the brain. Several strategies aim to overcome this obstacle and promote efficient and …

The blood–brain barrier (BBB) is a vital boundary between neural tissue and circulating
blood. The BBB's unique and protective features control brain homeostasis as well as ion …

Nano medicine had viewed countless breakthroughs in drug delivery implementations. The
main objective of nanotechnology application in delivering and carrying many promising …

Obtaining efficient drug delivery to the brain remains the biggest challenge for the
development of therapeutics to treat diseases of the central nervous system. The main …

In recent years, the researchers and drug designers have given growing attention to new
nanotechnology strategies to improve drug delivery to the central nervous system (CNS) …

As a result of ischemia or hemorrhage, blood supply to neurons is disrupted which
subsequently promotes a cascade of pathophysiological responses resulting in cell loss …

Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

Nanoparticles enable the delivery of a great variety of drugs including anticancer drugs,
analgesics, anti-Alzheimer's drugs, cardiovascular drugs, protease inhibitors, and several …

The central nervous system, one of the most delicate microenvironments of the body, is
protected by the blood‐brain barrier (BBB) regulating its homeostasis. BBB is a highly …