Transwoman elite athletes: their extra percentage relative to female physiology

AK Heather - International Journal of Environmental Research and …, 2022 - mdpi.com
There is increasing debate as to whether transwoman athletes should be included in the
elite female competition. Most elite sports are divided into male and female divisions …

Testosterone and aging male, a perspective from a developing country

B Nguyen Hoai, L Hoang, T Nguyen Cao… - The Aging …, 2023 - Taylor & Francis
Purpose Hypogonadism is associated with a wide range of physical and psychological
symptoms that can affect the overall health of men. However, in a developing country, there …

Uncovering the mechanism of the effects of Paeoniae Radix Alba on iron-deficiency anaemia through a network pharmacology-based strategy

X Ye, Y Deng, L Xia, H Ren, J Zhang - BMC complementary medicine and …, 2020 - Springer
Abstract Background Paeoniae Radix Alba, the root of the plant Paeonia lactiflora Pall, is a
common blood-enriching drug in traditional Chinese medicine. Its effectiveness in the …

Use of real‐world data to emulate a clinical trial and support regulatory decision making: assessing the impact of temporality, comparator choice, and method of …

D Abrahami, R Pradhan, H Yin, P Honig… - Clinical …, 2021 - Wiley Online Library
External controls have been primarily used in the setting of single‐arm trials of rare
diseases; their use in common diseases has not been readily investigated, nor is there …

Mechanisms responsible for reduced erythropoiesis during androgen deprivation therapy in men with prostate cancer

T Gagliano-Jucá, KM Pencina, T Ganz… - American Journal …, 2018 - journals.physiology.org
Androgen deprivation therapy (ADT) is a mainstay of treatment for prostate cancer (PCa). As
androgens stimulate erythropoiesis, ADT is associated with a reduction in hematocrit, which …

A dosimetric correlation between radiation dose to bone and reduction of hemoglobin levels after radiation therapy for prostate cancer

JB Fenlon, G Nelson, KM Teague, S Coleman… - International Journal of …, 2024 - Elsevier
Purpose The aim of this work was to investigate the correlation between dose to pelvic bone
marrow and anemia when treating prostate cancer (PC) with definitive radiation. Methods …

Linolenic acid stimulates eryptosis and hemolysis through oxidative stress and CK1α/MLKL: protective role of melatonin, urea, and polyethylene glycol

FH Alharthy, J Alsughayyir, MA Alfhili - Drug and Chemical …, 2024 - Taylor & Francis
Anticancer medications cause anemia in patients through ill-defined mechanisms, including
hemolysis and eryptosis. Although α-linolenic acid (ALA) possesses anticancer properties …

Impact of radiotherapy parameters on the risk of lymphopenia in urological tumors: A systematic review of the literature

W Danckaert, M Spaas, K Vandecasteele… - Radiotherapy and …, 2022 - Elsevier
Background We investigated how radiotherapy (RT) parameters may contribute to the risk of
lymphopenia in urological tumors and we discussed how this may impact clinical outcomes …

Synergistic immunotherapy targeting cancer-associated anemia: prospects of a combination strategy

T Yuan, Q Jia, B Zhu, D Chen, H Long - Cell Communication and Signaling, 2023 - Springer
Cancer-associated anemia promotes tumor progression, leads to poor quality of life in
patients with cancer, and even obstructs the efficacy of immune checkpoint inhibitors …

5‐α reductase inhibitors and the risk of anaemia among men with benign prostatic hyperplasia: A population‐based cohort study

HT Ayele, A Douros, KB Filion - British Journal of Clinical …, 2022 - Wiley Online Library
5‐α reductase inhibitors (5αRIs) are effective for the treatment of benign prostatic
hyperplasia (BPH). However, 5αRIs could lower levels of haemoglobin, increasing the risk of …