In many multicellular eukaryotes, heteromorphic sex chromosomes are responsible for
determining the sexual characteristics and reproductive functions of individuals. Sex …

Despite efforts to explore the genome of the malaria vector Anopheles gambiae, the Y
chromosome of this species remains enigmatic. The large number of repetitive and …

Understanding the sex determination pathway and its disruptions in mosquitoes is critical for
the effective control of disease vectors through genetic manipulations based on sex …

Differentiated sex chromosomes are frequently associated with major transcriptional
changes: the evolution of dosage compensation (DC) to equalize gene expression between …

Malaria-transmitting mosquitoes are extremely sexually dimorphic in their anatomy and
behaviour. Sex-specific gene expression in Anopheles gambiae is well-studied in adult …

The advent of the CRISPR/Cas9 technology permits the targeted editing of mosquito
genomes, ranging from site-directed mutagenesis of genes of interest yielding knockout …