Post-stroke cognitive impairment and dementia

NS Rost, A Brodtmann, MP Pase, SJ van Veluw… - Circulation …, 2022 - Am Heart Assoc
Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …

γ-Secretase in Alzheimer's disease

JY Hur - Experimental & molecular medicine, 2022 - nature.com
Alzheimer's disease (AD) is caused by synaptic and neuronal loss in the brain. One of the
characteristic hallmarks of AD is senile plaques containing amyloid β-peptide (Aβ). Aβ is …

Cognitive impairment after ischemic and hemorrhagic stroke: a scientific statement from the American Heart Association/American Stroke Association

N El Husseini, IL Katzan, NS Rost, ML Blake, E Byun… - Stroke, 2023 - Am Heart Assoc
Purpose: Cognitive impairment is a common consequence of stroke and has direct
implications for poststroke functioning and quality of life, including the ability to maintain a …

Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease

Y Inoue, F Shue, G Bu, T Kanekiyo - Molecular neurodegeneration, 2023 - Springer
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

Immune responses to stroke: mechanisms, modulation, and therapeutic potential

C Iadecola, MS Buckwalter… - The Journal of clinical …, 2020 - Am Soc Clin Investig
Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …

Vascular Cognitive Impairment and Dementia: JACC Scientific Expert Panel

C Iadecola, M Duering, V Hachinski, A Joutel… - Journal of the American …, 2019 - jacc.org
Cognitive impairment associated with aging has emerged as one of the major public health
challenges of our time. Although Alzheimer's disease is the leading cause of clinically …

[HTML][HTML] Vascular cognitive impairment (VCI)

T Rundek, M Tolea, T Ariko, EA Fagerli, CJ Camargo - Neurotherapeutics, 2023 - Elsevier
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts

NA Weaver, HJ Kuijf, HP Aben, J Abrigo… - The Lancet …, 2021 - thelancet.com
Background Post-stroke cognitive impairment (PSCI) occurs in approximately half of people
in the first year after stroke. Infarct location is a potential determinant of PSCI, but a …

European Stroke Organisation and European Academy of Neurology joint guidelines on post-stroke cognitive impairment

TJ Quinn, E Richard, Y Teuschl… - European stroke …, 2021 - journals.sagepub.com
The optimal management of post-stroke cognitive impairment remains controversial. These
joint European Stroke Organisation (ESO) and European Academy of Neurology (EAN) …

Incidence and prevalence of dementia associated with transient ischaemic attack and stroke: analysis of the population-based Oxford Vascular Study

ST Pendlebury, PM Rothwell - The Lancet Neurology, 2019 - thelancet.com
Background Risk of dementia after stroke is a major concern for patients and carers.
Reliable data for risk of dementia, particularly after transient ischaemic attack or minor …