The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …

Background: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive
syndromes is a significant determinant of short-and long-term outcomes. Although …

A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Heart failure is a growing health issue as a negative consequence of improved survival
upon myocardial infarction, unhealthy lifestyle, and the ageing of our population. The large …

Braunwald Cell-Based Therapy in Cardiac Regeneration 133 therapy rarely uses a single
administration of a drug and it would seem logical to deliver cells repeatedly in treating a …

Diseases of the preterm newborn such as bronchopulmonary dysplasia, necrotizing
enterocolitis, cerebral palsy, and hypoxic-ischemic encephalopathy continue to be major …

Right ventricular fibrosis is a stress response, predominantly mediated by cardiac
fibroblasts. This cell population is sensitive to increased levels of pro-inflammatory …

Background: Congenital heart disease (CHD) constitutes the most prevalent and
heterogeneous group of congenital anomalies. Although surgery remains the gold standard …

Heart failure (HF) after myocardial infarction (MI) due to blockage of coronary arteries is a
major public health issue. MI results in massive loss of cardiac muscle due to ischemia …

Rationale: Intracoronary administration of cardiosphere-derived cells (CDCs) in patients with
single ventricles resulted in a short-term improvement in cardiac function. Objective: To test …