Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction

I Hope, MP Martin, MJ Waring, MEM Noble, JA Endicott… - bioRxiv, 2024 - biorxiv.org
Protein-protein interaction sites (PPIs) are potentially more selective therapeutic binding
sites than protein substrate binding sites. PPIs include distinct regions frequently called" …