▪ Abstract The unicellular green alga Chlamydomonas offers a simple life cycle, easy
isolation of mutants, and a growing array of tools and techniques for molecular genetic …

Sperm motility is generated by a highly organized, microtubule-based structure, called the
axoneme, which is constructed from approximately 250 proteins. Recent studies have …

Motile cilia and flagella beat rhythmically on the surface of cells to power the flow of fluid and
to enable spermatozoa and unicellular eukaryotes to swim. In humans, defective ciliary …

Dr. Harris has played a major role in the development of this organism as a model system.
Her previous version of the Chlamydomonas Sourcebook which published in 1989, has …

Cell Movements vividly describes how complex movements can arise from the properties
and behaviors of biological molecules. This second edition is updated throughout with …

In humans, seven evolutionarily conserved genes that cause the cilia-related disorder
Bardet-Biedl syndrome (BBS) encode proteins that form a complex termed the BBSome. The …

Sperm motility is necessary for the transport of male DNA to eggs in species with both
external and internal fertilization. Flagella comprise several proteins for generating and …

Cilia and flagella are found on a variety of cell types, ranging from single cell protozoa and
sperm to the ciliated epithelia of the respiratory and reproductive tracts. Despite this …

Bardet–Biedl syndrome (BBS) is a ciliopathy resulting from defects in the BBSome, a
conserved protein complex. BBSome mutations affect ciliary membrane composition …

The 9+ 2 microtubule arrangement is the most conserved axonemal configuration,
suggesting that this organization has been retained under evolutionary pressure for crucial …