Microencapsulation techniques, factors influencing encapsulation efficiency

NVN Jyothi, PM Prasanna, SN Sakarkar… - Journal of …, 2010 - Taylor & Francis
Microencapsulation is one of the quality preservation techniques of sensitive substances
and a method for production of materials with new valuable properties. Microencapsulation …

Polymer microspheres for controlled drug release

S Freiberg, XX Zhu - International journal of pharmaceutics, 2004 - Elsevier
Polymer microspheres can be employed to deliver medication in a rate-controlled and
sometimes targeted manner. Medication is released from a microsphere by drug leaching …

[图书][B] Handbook of encapsulation and controlled release

M Mishra - 2015 - books.google.com
Written at a level comprehensible to non-experts, this handbook covers the current state of
encapsulation and controlled released technologies, presenting the fundamental processes …

Control of encapsulation efficiency and initial burst in polymeric microparticle systems

Y Yeo, K Park - Archives of pharmacal research, 2004 - Springer
Initial burst is one of the major challenges in protein-encapsulated microparticle systems.
Since protein release during the initial stage depends mostly on the diffusional escape of the …

Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres

S Mao, J Xu, C Cai, O Germershaus, A Schaper… - International journal of …, 2007 - Elsevier
Using fluorescein isothiocyanate labeled dextran (FITC-dextran 40, FD40) as a hydrophilic
model compound, microspheres were prepared by a WOW double emulsion technique …

Influence of the poly (lactide-co-glycolide) type on the leuprolide release from in situ forming microparticle systems

X Luan, R Bodmeier - Journal of Controlled Release, 2006 - Elsevier
The objective was to investigate the influence of poly (lactide-co-glycolide)(PLGA) type
(molecular weight and end-group functionality) on the leuprolide release from in situ forming …

Effect of manufacturing variables and raw materials on the composition-equivalent PLGA microspheres for 1-month controlled release of leuprolide

J Zhou, J Walker, R Ackermann, K Olsen… - Molecular …, 2020 - ACS Publications
The 1-month Lupron Depot (LD) is a 75/25 acid-capped poly (lactic-co-glycolic acid)(PLGA)
microsphere product encapsulating water-soluble leuprolide acetate with no generic …

Development of enteric submicron particle formulation of papain for oral delivery

M Sharma, V Sharma, AK Panda… - International journal of …, 2011 - Taylor & Francis
Background Particulate systems have received increasing attention for oral delivery of
biomolecules. The objective of the present study was to prepare submicron particulate …

Variables influencing the drug entrapment efficiency of microspheres: A pharmaceutical review

RC Dhakar, SD Maurya, BPS Sagar, S Bhagat… - Der Pharmacia …, 2010 - papers.ssrn.com
Novel drug delivery systems have several advantages over conventional multi dose therapy.
Much research effort in developing novel drug delivery system has been focused on …

Key parameters affecting the initial release (burst) and encapsulation efficiency of peptide-containing poly (lactide-co-glycolide) microparticles

X Luan, M Skupin, J Siepmann, R Bodmeier - International journal of …, 2006 - Elsevier
The objective of this study was to identify key variables affecting the initial release (burst)
and the encapsulation of leuprolide acetate-containing poly (lactide-co-glycolide)(PLGA) …