Review of a new bone tumor therapy strategy based on bifunctional biomaterials

J Liao, R Han, Y Wu, Z Qian - Bone research, 2021 - nature.com
Bone tumors, especially those in osteosarcoma, usually occur in adolescents. The standard
clinical treatment includes chemotherapy, surgical therapy, and radiation therapy …

Electrospun biomimetic nanofibrous scaffolds: a promising prospect for bone tissue engineering and regenerative medicine

S Anjum, F Rahman, P Pandey, DK Arya… - International Journal of …, 2022 - mdpi.com
Skeletal-related disorders such as arthritis, bone cancer, osteosarcoma, and osteoarthritis
are among the most common reasons for mortality in humans at present. Nanostructured …

Bone‐targeted exosomes: strategies and applications

J Wang, X Li, S Wang, J Cui, X Ren… - Advanced healthcare …, 2023 - Wiley Online Library
As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …

Targeting nanoparticles for diagnosis and therapy of bone tumors: Opportunities and challenges

X Gao, L Li, X Cai, Q Huang, J Xiao, Y Cheng - Biomaterials, 2021 - Elsevier
A variety of targeted nanoparticles were developed for the diagnosis and therapy of
orthotopic and metastatic bone tumors during the past decade. This critical review will focus …

Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis

S Zhu, W Chen, A Masson, YP Li - Cell Discovery, 2024 - nature.com
The initiation of osteogenesis primarily occurs as mesenchymal stem cells undergo
differentiation into osteoblasts. This differentiation process plays a crucial role in bone …

Nanomedicines accessible in the market for clinical interventions

V Gadekar, Y Borade, S Kannaujia, K Rajpoot… - Journal of Controlled …, 2021 - Elsevier
Nanomedicines refers to nanotechnology inspired pharmaceutical products often referred to
as 'nanopharmaceuticals.'It has displayed commendable potential in enhancing therapeutic …

The relationship between bone marrow adipose tissue and bone metabolism in postmenopausal osteoporosis

J Li, X Chen, L Lu, X Yu - Cytokine & growth factor reviews, 2020 - Elsevier
Postmenopausal osteoporosis (PMOP) is a prevalent skeletal disorder associated with
menopause-related estrogen withdrawal. PMOP is characterized by low bone mass …

Bone-targeted nanoparticle drug delivery system: an emerging strategy for bone-related disease

Y Chen, X Wu, J Li, Y Jiang, K Xu, J Su - Frontiers in Pharmacology, 2022 - frontiersin.org
Targeted delivery by either systemic or local targeting of therapeutics to the bone is an
attractive treatment for various bone metabolism diseases such as osteoporosis …

Emerging nano-scale delivery systems for the treatment of osteoporosis

AP Dayanandan, WJ Cho, H Kang, AB Bello… - Biomaterials …, 2023 - spj.science.org
Osteoporosis is a pathological condition characterized by an accelerated bone resorption
rate, resulting in decreased bone density and increased susceptibility to fractures …

Polymer incorporated magnetic nanoparticles: Applications for magnetoresponsive targeted drug delivery

F Sharifianjazi, M Irani, A Esmaeilkhanian… - Materials Science and …, 2021 - Elsevier
Efficient release and the delivery of active substances are necessary for diverse medical
applications including biosensors, biotechnology, and medical therapy. Meanwhile, drug …