Molecular Actions of PPARα in Lipid Metabolism and Inflammation

N Bougarne, B Weyers, SJ Desmet, J Deckers… - Endocrine …, 2018 - academic.oup.com
Peroxisome proliferator–activated receptor α (PPAR α) is a nuclear receptor of clinical
interest as a drug target in various metabolic disorders. PPAR α also exhibits marked anti …

The novel role of PPAR alpha in the brain: promising target in therapy of Alzheimer's disease and other neurodegenerative disorders

S Wójtowicz, AK Strosznajder, M Jeżyna… - Neurochemical …, 2020 - Springer
Peroxisome proliferator activated receptor alpha (PPAR-α) belongs to the family of ligand-
regulated nuclear receptors (PPARs). These receptors after heterodimerization with retinoid …

Phytol: A review of biomedical activities

MT Islam, ES Ali, SJ Uddin, S Shaw, MA Islam… - Food and chemical …, 2018 - Elsevier
Phytol (PYT) is a diterpene member of the long-chain unsaturated acyclic alcohols. PYT and
some of its derivatives, including phytanic acid (PA), exert a wide range of biological effects …

A review on endocrine disruptors and their possible impacts on human health

ER Kabir, MS Rahman, I Rahman - Environmental toxicology and …, 2015 - Elsevier
Endocrine disruption is a named field of research which has been very active for over 10
years, although the effects of endocrine disruptors in wildlife have been studied mainly in …

Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications-a review

B Grygiel-Górniak - Nutrition journal, 2014 - Springer
Peroxisome proliferator-activated receptors are expressed in many tissues, including
adipocytes, hepatocytes, muscles and endothelial cells; however, the affinity depends on the …

PPAR gamma gene–a review

C Janani, BDR Kumari - … & Metabolic Syndrome: Clinical Research & …, 2015 - Elsevier
Peroxisome proliferator-activated receptor gamma (PPARγ) has been the focus of intense
research because ligands for this receptor have emerged as potent insulin sensitizers used …

Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin

SN Goyal, CP Prajapati, PR Gore, CR Patil… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …

Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases

FM Gutierrez-Mariscal, AP Arenas-de Larriva… - International journal of …, 2020 - mdpi.com
Apart from its main function in the mitochondria as a key element in electron transport,
Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant …

Endocrine disruptors: from endocrine to metabolic disruption

C Casals-Casas, B Desvergne - Annual review of physiology, 2011 - annualreviews.org
Synthetic chemicals currently used in a variety of industrial and agricultural applications are
leading to widespread contamination of the environment. Even though the intended uses of …

PPARs: fatty acid sensors controlling metabolism

L la Cour Poulsen, M Siersbæk, S Mandrup - Seminars in cell & …, 2012 - Elsevier
The peroxisome proliferator activated receptors (PPARs) are nuclear receptors that play key
roles in the regulation of lipid metabolism, inflammation, cellular growth, and differentiation …