The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

Trophoblast stem cells (TSC) are the precursors of the differentiated cells of the placenta. In
the mouse, TSC can be derived from outgrowths of either blastocyst polar trophectoderm …

Embryogenesis necessitates harmonious coordination between embryonic and
extraembryonic tissues. Although stem cells of both embryonic and extraembryonic origins …

Embryonic and extra-embryonic lineages are separated at the blastocyst stage in the mouse
at the onset of implantation but well ahead of implantation in most mammals. To provide …

Here, we report that a chemical cocktail (LCDM: leukemia inhibitory factor [LIF], CHIR99021,
dimethinedene maleate [DiM], minocycline hydrochloride), previously developed for …

Embryonic stem (ES) cell lines provide an invaluable research tool for genetic engineering,
developmental biology and disease models. These cells can be maintained indefinitely in …

The main roles of placentas include physical protection, nutrient and oxygen import, export
of gasses and fetal waste products, and endocrinological regulation. In addition to physical …

Uterine-derived factors are essential for conceptus development and secretion of the
maternal recognition-of-pregnancy factor, interferon-τ (IFNT), in ruminant species. The …

The overall aim of this work was to examine the expression profiles for fibroblast growth
factor receptors (FGFRs) and describe their biological importance during bovine pre-and …

Embryonic losses constitute a major burden for reproductive efficiency of farm animals.
Pregnancy losses in ungulate species, which include cattle, pigs, sheep and goats, majorly …